Evidence map›Paper›PMID 35602005›Full record

ArticleCurrent research in toxicology2022

Assessment of the effects of organic vs. inorganic arsenic and mercury in

Jessica Camacho, Aline de Conti, Igor P Pogribny, Robert L Sprando, Piper Reid Hunt

Open access · goldAbstract read
In one paragraph

Article in Current research in toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. High-Throughput Toxicity Screening withEnvironmental science & technology · 2026
    Review
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  5. Review
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  9. Reproductive-Toxicity-Related Endpoints inJournal of developmental biology · 2023
    Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jessica CamachoFood and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Applied Research and Safety Assessment, 8301 Muirkirk Road, Laurel, MD 20708, United States.
Aline de ContiFood and Drug Administration, National Center for Toxicological Research, 3900 NCTR Rd, Jefferson, AR 72079, United States.
Igor P PogribnyFood and Drug Administration, National Center for Toxicological Research, 3900 NCTR Rd, Jefferson, AR 72079, United States.
Robert L SprandoFood and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Applied Research and Safety Assessment, 8301 Muirkirk Road, Laurel, MD 20708, United States.
Piper Reid HuntFood and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Applied Research and Safety Assessment, 8301 Muirkirk Road, Laurel, MD 20708, United States.
Center for Food Safety and Applied Nutrition · USNational Center for Toxicological Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposures to mercury and arsenic are known to pose significant threats to human health. Effects specific to organic vs. inorganic forms of these toxic elements are less understood however, especially for organic dimethylarsinic acid (DMA), which has recently been detected in pups of rodent dams orally exposed to inorganic sodium (meta)arsenite (NaAsO2).

Indexed as

Alternative Toxicity ModelArsenicDEGs, Differentially Expressed GenesDMA, dimethylarsinic acidER, endoplasmic reticulumEXT, extinction (a measure of optical density)GO, gene ontologyHgCl2, mercury(ii) chlorideiAs, inorganic arsenicInorganicL1, first larval stage C. elegansLD50, the median lethal dose per kilogram of body weightLOEL, lowest observed effect levelmeHgCl, methylmercury chlorideMercuryNaAsO2, sodium (meta)arseniteNOEL, no observed effect levelOrganicOxStrR, Oxidative Stress ResponsePredictive ToxicologyTOF, time of flight (a measure of size)UPR, Unfolded Protein Response

Identifiers

PMID35602005
PMCPMC9118485
OpenAlexW4229335997

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.