ArticleThe Plant cell2022
A molecular framework of ethylene-mediated fruit growth and ripening processes in tomato.
Article in The Plant cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed, 120 citations in OpenAlex.
- Improving the Postharvest Storage and Quality of Tomatoes (Molecules (Basel, Switzerland) · 2026Article
- Ethylene networking in fruit ripening: molecular mechanisms, hormone crosstalk, climate interactions, and postharvest management.Plant cell reports · 2026Review
- PbrIDD2-PbrAPX14 Module Functions in the Ethylene-Mediated Ripening and Senescence Process of Pear Fruit.Plant biotechnology journal · 2026Article
- Genome Wide Association Study Reveals Novel Loci Controlling Agronomic Traits in Tomato (Solanum lycopersicum L.).Biochemical genetics · 2026Article
- Regulation of the growth-to-ripening transition in tomato fruits by energy charge involving SlATP-PRT and SlAPRT1.Molecular horticulture · 2026Article
- SlERF-RD1 acts as a developmental coordinator integrating plant canopy architecture and the ethylene-mediated ripening cascade in tomato.Plant cell reports · 2026Article
- The MdERF17-MdbHLH149 Module Mediates Ethylene-Induced Starch Degradation Through the Transcriptional Repression of α-Amylase MdAMY1 in Apple.Plant biotechnology journal · 2026Article
- Single-nucleus transcriptome profiling unveils cell-type-specific ethylene and TOR signaling in tomato.Horticulture research · 2026Article
- Fruit respiration: putting alternative pathways into perspective.The New phytologist · 2026Review
- The carotenoids metabolism during tomato fruit ripening: insights into multi-level regulatory network.BMC plant biology · 2026Review
- Integrated Phylogenomic and Expression Analyses Reveal Lineage-Specific Loss of the Mβ Subfamily and Regulatory Diversification of MADS-Box Genes in Pepper.Plants (Basel, Switzerland) · 2026Article
- Type one protein phosphatases (TOPPs) catalyze EIN2 dephosphorylation to regulate ethylene signaling inScience advances · 2026Article
- Ethylene promotes branch formation but inhibits tendril development in cucumber.Nature communications · 2025Article
- Transcriptional control of tomato fruit development and ripening.Journal of experimental botany · 2025Review
- The 14-3-3 Protein SlTFT1 Accelerates Tomato Fruit Ripening by Binding and Stabilising YFT1 in the Ethylene Signalling Pathway.Plant biotechnology journal · 2025Article
- EIN3-binding F-box protein SlEBF3 modulates resistance againstHorticulture research · 2025Article
- A comprehensive model of tomato fruit ripening regulation by the transcription factors NOR-like1, NAC-NOR, and MADS-RIN.Plant physiology · 2025Article
- ERF100 regulated by ERF28 and NOR controls pectate lyase 7, modulating fig (Ficus carica L.) fruit softening.Plant biotechnology journal · 2025Article
- Transcriptome profiling reveals the regulatory mechanisms of AsA (ascorbic acid) and flavonoid synthesis and metabolic processes in fruit development of Ribes nigrum L.Molecular genetics and genomics : MGG · 2025Article
- Ethylene promotes anthocyanin synthesis in 'Viviana' lily via the LvMYB5-LvERF113-LvMYB1 module.Horticulture research · 2025Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the role of ethylene in tomato (Solanum lycopersicum) fruit ripening has been intensively studied, its role in tomato fruit growth remains poorly understood. In addition, the relationship between ethylene and the developmental factors NON-RIPENING (NOR) and RIPENING INHIBITOR (RIN) during ripening is under debate. Here, we carried out comprehensive genetic analyses of genome-edited mutants of tomato ETHYLENE INSENSITIVE 2 (SlEIN2), four EIN3-like genes (SlEIL1-4), and three EIN3 BINDING F-box protein genes (SlEBF1-3). Both slein2-1 and the high-order sleil mutant (sleil1 sleil2 sleil3/SlEIL3 sleil4) showed reduced fruit size, mainly due to decreased auxin biosynthesis. During fruit maturation, slein2 mutants displayed the complete cessation of ripening, which was partially rescued by slebf1 but not slebf2 or slebf3. We also discovered that ethylene directly activates the expression of the developmental genes NOR, RIN, and FRUITFULL1 (FUL1) via SlEIL proteins. Indeed, overexpressing these genes partially rescued the ripening defects of slein2-1. Finally, the signal intensity of the ethylene burst during fruit maturation was intimately connected with the progression of full ripeness. Collectively, our work uncovers a critical role of ethylene in fruit growth and supports a molecular framework of ripening control in which the developmental factors NOR, RIN, and FUL1 act downstream of ethylene signaling.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.