Evidence map›Paper›PMID 35604839›Full record

ArticleAnalytical chemistry2022

FT-ICR Mass Spectrometry Imaging at Extreme Mass Resolving Power Using a Dynamically Harmonized ICR Cell with 1ω or 2ω Detection.

Mathieu Tiquet, Raphaël La Rocca, Stefan Kirnbauer, Samuele Zoratto, Daan Van Kruining, Loïc Quinton, Gauthier Eppe, Pilar Martinez-Martinez, Martina Marchetti-Deschmann, Edwin De Pauw and 1 more

Abstract read
In one paragraph

Article in Analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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  5. Article
  6. Article
  7. Organ-resolved lipid mapping inFrontiers in chemistry · 2025
    Article
  8. Article
  9. Imaging plant metabolism in situ.Journal of experimental botany · 2024
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mathieu TiquetMass Spectrometry Laboratory, MolSys Research Unit, University of Liège, Allée de la Chimie 6-Quartier Agora, 4000 Liège, Belgium.ORCID 0000-0002-9873-0065
Raphaël La RoccaMass Spectrometry Laboratory, MolSys Research Unit, University of Liège, Allée de la Chimie 6-Quartier Agora, 4000 Liège, Belgium.ORCID 0000-0003-3388-3041
Stefan KirnbauerInstitute of Chemical Technologies and Analytics, TU Wien (Vienna University of Technology), Getreidemarkt 9/164, 1060 Vienna, Austria.
Samuele ZorattoInstitute of Chemical Technologies and Analytics, TU Wien (Vienna University of Technology), Getreidemarkt 9/164, 1060 Vienna, Austria.
Daan Van KruiningDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229ER Maastricht, the Netherlands.
Loïc QuintonMass Spectrometry Laboratory, MolSys Research Unit, University of Liège, Allée de la Chimie 6-Quartier Agora, 4000 Liège, Belgium.ORCID 0000-0001-8153-9590
Gauthier EppeMass Spectrometry Laboratory, MolSys Research Unit, University of Liège, Allée de la Chimie 6-Quartier Agora, 4000 Liège, Belgium.ORCID 0000-0002-4821-3115
Pilar Martinez-MartinezDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229ER Maastricht, the Netherlands.
Martina Marchetti-DeschmannInstitute of Chemical Technologies and Analytics, TU Wien (Vienna University of Technology), Getreidemarkt 9/164, 1060 Vienna, Austria.ORCID 0000-0002-8060-7851
Edwin De PauwMass Spectrometry Laboratory, MolSys Research Unit, University of Liège, Allée de la Chimie 6-Quartier Agora, 4000 Liège, Belgium.ORCID 0000-0003-3475-1315
Johann FarMass Spectrometry Laboratory, MolSys Research Unit, University of Liège, Allée de la Chimie 6-Quartier Agora, 4000 Liège, Belgium.ORCID 0000-0003-1208-6262

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MALDI mass spectrometry imaging (MALDI MSI) is a powerful analytical method for achieving 2D localization of compounds from thin sections of typically but not exclusively biological samples. The dynamically harmonized ICR cell (ParaCell) was recently introduced to achieve extreme spectral resolution capable of providing the isotopic fine structure of ions detected in complex samples. The latest improvement in the ICR technology also includes 2ω detection, which significantly reduces the transient time while preserving the nominal mass resolving power of the ICR cell. High-resolution MS images acquired on FT-ICR instruments equipped with 7T and 9.4T superconducting magnets and the dynamically harmonized ICR cell operating at suboptimal parameters suffered severely from the pixel-to-pixel shifting of

Indexed as

CyclotronsDiagnostic ImagingFourier AnalysisIonsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationIons

Identifiers

PMID35604839
PMCPMC9260710

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.