Evidence map›Paper›PMID 35606743›Full record

ArticleBMC public health2022

Seroprevalence of SARS-CoV-2 antibody among urban Iranian population: findings from the second large population-based cross-sectional study.

Mohammad Zamani, Hossein Poustchi, Zahra Mohammadi, Sahar Dalvand, Maryam Sharafkhah, Seyed Abbas Motevalian, Saeid Eslami, Amir Emami, Mohammad Hossein Somi, Jamshid Yazdani-Charati and 24 more

Abstract read
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Mohammad Zamani *Digestive Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, 14117-13135, Iran.
Hossein Poustchi *Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Zahra MohammadiLiver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Sahar DalvandLiver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Maryam SharafkhahLiver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Seyed Abbas MotevalianResearch Center for Addiction and Risky Behaviors (ReCARB), Psychosocial Health Research Institute, Iran University of Medical Sciences, Tehran, Iran.
Saeid EslamiPharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Amir EmamiMicrobiology Department, Burn & Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Hossein SomiLiver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Jamshid Yazdani-CharatiDepartment of Biostatistics, Health Sciences Research Center, Addiction Institute, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.
Nader SakiHearing Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Manoochehr KaramiDepartment of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
Farid NajafiResearch Center for Environmental Determinants of Health, School of Public Health, Kermanshah UMS, Kermanshah, Iran.
Iraj MohebbiSocial Determinants of Health Center, Urmia University of Medical Sciences, Urmia, Iran.
Nasrollah VeisiKurdistan University of Medical Sciences, Sanandaj, Iran.
Ahmad HormatiGastroenterology and Hepatology Disease Research Center, Qom University of Medical Science, Qom, Iran.
Farhad PourfarziDigestive Disease Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.
Reza GhadimiSocial Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Alireza Ansari-MoghaddamHealth Promotion Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Hamid SharifiHIV/STI Surveillance Research Center and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Gholamreza RoshandelGolestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran.
Fariborz Mansour-GhanaeiDivision of Gastroenterology & Hepatology, Gastrointestinal & Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Farahnaz JoukarGastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Amaneh ShayanradLiver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Sareh EghtesadLiver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ahmadreza NiavaraniDigestive Oncology Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Alireza DelavariDigestive Oncology Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Soudeh KavehLiver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Akbar FeizesaniLiver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Melineh MarkarianDigestive Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, 14117-13135, Iran.
Fatemeh ShafighianDigestive Oncology Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Alireza SadjadiDigestive Oncology Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Maryam DarvishianCancer Control Research, BC Cancer Research Centre, Vancouver, BC, Canada.
Reza MalekzadehDigestive Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, 14117-13135, Iran. dr.reza.malekzadeh@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe first large serosurvey in Iran found a SARS-CoV-2 antibody seroprevalence of 17.1% among the general population in the first wave of the epidemic by April, 2020. The purpose of the current study was to assess the seroprevalence of COVID-19 infection among Iranian general population after the third wave of the disease.

methodsThis population-based cross-sectional study was conducted on 7411 individuals aged ≥10 years old in 16 cities across 15 provinces in Iran between January and March, 2021. We randomly sampled individuals registered in the Iranian electronic health record system based on their national identification numbers and invited them by telephone to a healthcare center for data collection. Presence of SARS-CoV-2-specific IgG and IgM antibodies was assessed using the SARS-CoV-2 ELISA kits. The participants were also asked about their recent COVID-19-related symptoms, including cough, fever, chills, sore throat, headache, dyspnea, diarrhea, anosmia, conjunctivitis, weakness, myalgia, arthralgia, altered level of consciousness, and chest pain. The seroprevalence was estimated after adjustment for population weighting and test performance.

resultsThe overall population-weighted seroprevalence adjusted for test performance was 34.2% (95% CI 31.0-37.3), with an estimated 7,667,874 (95% CI 6,950,412-8,362,915) infected individuals from the 16 cities. The seroprevalence varied between the cities, from the highest estimate in Tabriz (39.2% [95% CI 33.0-45.5]) to the lowest estimate in Kerman (16.0% [95% CI 10.7-21.4]). In the 16 cities studied, 50.9% of the seropositive individuals did not report a history of symptoms suggestive of COVID-19, implying an estimation of 3,902,948 (95% CI 3,537,760-4,256,724) asymptomatic infected individuals.

conclusionsNearly one in three individuals were exposed to SARS-CoV-2 in the studied cities by March 2021. The seroprevalence increased about two-fold between April, 2020, and March, 2021.

Indexed as

COVID-19SARS-CoV-2Antibodies, ViralChildCross-Sectional StudiesHumansImmunoglobulin GIranSeroepidemiologic StudiesAntibodies, ViralImmunoglobulin GCOVID-19General populationInfectionSARS-CoV-2Seroprevalence

Identifiers

PMID35606743
PMCPMC9125542

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.