Evidence map›Paper›PMID 35606780›Full record

ArticleJournal of cardiothoracic surgery2022

Single center first year experience and outcomes with Impella 5.5 left ventricular assist device.

Joanna R Rock, Cynthia A Kos, Anthony Lemaire, Hirohisa Ikegami, Mark J Russo, Danyaal Moin, Kenneth Dulnuan, Deepa Iyer

Abstract read
In one paragraph

Article in Journal of cardiothoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joanna R RockRutgers University-Robert Wood Johnson Medical School, New Brunswick, NJ, USA. Jr1472@rwjms.rutgers.edu.ORCID http://orcid.org/0000-0002-2050-5124
Cynthia A KosRutgers University-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Anthony LemaireRutgers University-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Hirohisa IkegamiRutgers University-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Mark J RussoRutgers University-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Danyaal MoinRutgers University-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Kenneth DulnuanRutgers University-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Deepa IyerRutgers University-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Impella 5.5® was approved by the FDA for use for mechanical circulatory support up to 14 days in late 2019 at limited centers in the United States. Our single center's experience with Impella 5.5® can expand the overall understanding for achieving successful patient outcomes as well as provide support for the expansion of its FDA-approved use.

methodsThis study is an IRB-approved single-center retrospective cohort analysis of hospitalized adult patient characteristics and outcomes in cases where the Impella 5.5® was utilized for mechanical circulatory support.

resultsA total of 26 implanted Impella 5.5® devices were identified in 24 hospitalized patients at our institution from January 2020 to January 2021. The overall survival rate during index hospitalization was 75%. Eleven Impella 5.5® devices were identified in 10 patients with an average device implantation greater than 14 days. Average device implantation for this subgroup was 27 days with a range of 15-80 days. Survival rate for Impella 5.5® use greater than 14 days was 67%. In the entire cohort and subgroup of device implantation > 14 days, evidence of end organ damage improved with Impella 5.5® use. Complications in our cohort and subgroup of device implantation > 14 days were similar to previously reported complication incidence of axillary inserted LVAD devices.

conclusionsOur institution's experience with the Impella 5.5® has been strongly positive with favorable outcomes and helps to establish the Impella 5.5® as a viable option for mechanical circulatory support beyond 14 days.

Indexed as

Heart-Assist DevicesAdultCohort StudiesHumansRetrospective StudiesShock, CardiogenicTreatment OutcomeAdvanced heart failureCardiogenic shockCardiomyopathyImpellaLeft ventricular assist devicesMechanical circulatory support

Identifiers

PMID35606780
PMCPMC9128113

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.