Evidence map›Paper›PMID 35615400›Full record

ArticleDisease markers2022

Functional Analysis of Serum Long Noncoding RNAs in Patients with Atrial Fibrillation.

Qi Zhang, Jun Wang, Ying Wang, Ji-Meng Yang, Hai-Cui Dong, Di Xu

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

  • Retraction · 2023-07-19Concerns/Issues about Data · Concerns/Issues about Results and/or Conclusions · Concerns/Issues about Referencing/Attributions · Concerns/Issues about Peer Review · Informed/Patient Consent - None/Withdrawn · Investigation by Journal/Publisher · Investigation by Third Party · Lack of IRB/IACUC Approval and/or Compliance · Paper Mill · Computer-Aided Content or Computer-Generated Content · Unreliable Results and/or Conclusions · · See also: https://pubpeer.com/publications/DC22EBA2141BACDED565BFFD667C91
  • Retracted
5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qi ZhangDepartment of Cardiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Jun WangDepartment of Cardiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Ying WangDepartment of Cardiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Ji-Meng YangDepartment of Cardiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Hai-Cui DongDepartment of Cardiology, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Di XuDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0003-1404-2626
Nanjing Medical University · CNJiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Long noncoding RNAs (lncRNAs) are closely related to diverse diseases. However, its role in atrial fibrillation (AF) pathogenesis needs further exploration. Design: We performed microarray analysis on the serum samples from 70 healthy volunteers and 70 AF patients. This study was aimed at detecting the levels of serum lncRNAs and mRNAs and bioinformatically analyze them to establish potential marker(s) for AF diagnosis. Receiver operating curve (ROC) and area under the curve (AUC) were employed to address the AF diagnostic power of lncRNAs. Results: In the AF serum samples, 753 lncRNAs and 802 mRNAs ( Conclusions: Our work highlights the role of lncRNAs in AF pathogenesis and provides a novel serum biomarker for AF diagnosis.

Indexed as

Atrial FibrillationRNA, Long NoncodingBiomarkersGene Expression ProfilingHumansPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktRNA, MessengerBiomarkersPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktRNA, Long NoncodingRNA, Messenger

Identifiers

PMID35615400
PMCPMC9126683
OpenAlexW4280623283

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.