Evidence map›Paper›PMID 35616298›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2022

Design, synthesis, and biological evaluation of triazole-pyrimidine-methylbenzonitrile derivatives as dual A

Zhi Li, Lijuan Kou, Xinzhen Fu, Zeping Xie, Maolei Xu, Lin Guo, Tiantian Lin, Shizhou Gong, Shumin Zhang, Ming Liu

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhi LiSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Lijuan KouSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Xinzhen FuSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Zeping XieSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Maolei XuSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Lin GuoSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Tiantian LinLuye Pharma Group, Yantai, China.
Shizhou GongLuye Pharma Group, Yantai, China.
Shumin ZhangSchool of Pharmacy, Binzhou Medical University, Yantai, China.
Ming LiuSchool of Pharmacy, Binzhou Medical University, Yantai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of novel dual A

Indexed as

Purinergic P1 Receptor AntagonistsTriazolesAdenosine A2 Receptor AntagonistsMolecular Docking SimulationPyrimidinesReceptor, Adenosine A2AReceptor, Adenosine A2BAdenosine A2 Receptor AntagonistsPurinergic P1 Receptor AntagonistsPyrimidinesReceptor, Adenosine A2AReceptor, Adenosine A2BTriazolesDual A2A/A2B adenosine receptor antagonistsmethylbenzonitrilepharmacokineticsquinolineT cell activation

Identifiers

PMID35616298
PMCPMC9154793

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.