ReviewInternational journal of physiology, pathophysiology and pharmacology2022
The long-term renal effects of short periods of unilateral ureteral obstruction.
Review in International journal of physiology, pathophysiology and pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 10 citations in OpenAlex.
- Influence of primary language on follow-up after emergency department visits for acute renal colic: evidence from an ethnically diverse urban cohort.World journal of urology · 2026Article
- Pre-treatment with 2-mercaptoethanol attenuates ferroptosis-associated redox imbalance and inflammatory responses, but not tubulointerstitial fibrosis, in unilateral ureteral obstruction.Pharmacological reports : PR · 2026Article
- Membranous remodeling of basal infoldings in attenuated epithelial cells of dilated renal tubules under unilateral ureteral obstruction (UUO) in adult mouse kidney.Histology and histopathology · 2026Article
- Article
- Identification of Stable Housekeeping Genes for miRNA Expression Studies in a Mouse Unilateral Ureteral Obstruction Model.Biochemical genetics · 2026Article
- Quality assessment of robotic repair of benign ureteral strictures A Canadian, single-center experience.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026Article
- Two-step postoperative ultrasound for early detection of ureteral obstruction after benign hysterectomy.BMC women's health · 2026Article
- Isorhamnetin attenuates renal interstitial fibrosis by targeting TWEAK/Fn14-mediated epithelial-mesenchymal transition.Frontiers in immunology · 2025Article
- Case Report: Iatrogenic intraperitoneal hematoma compresses the ureters leading to urogenic sepsis.Frontiers in medicine · 2025Article
- Utilizing computed tomography-based renal parenchymal volumes to calculate split renal function in patients with ureteral stricture disease.World journal of urology · 2024Article
- Obstructive uropathy: Overview of the pathogenesis, etiology and management of a prevalent cause of acute kidney injury.World journal of nephrology · 2024Review
- A Pelvic Abscess and a Pelvic Stone Secondary to a Ureteral Calculus.Case reports in radiology · 2024Article
- Elevated hydrostatic pressure disturbs expression of growth factors in human renal epithelial cells.PloS one · 2024Article
- The role of N-methyladenosine modification in acute and chronic kidney diseases.Molecular medicine (Cambridge, Mass.) · 2023Review
- The effect of tannic acid on renal renin-angiotensin signaling pathway in a model of unilateral ureteral obstruction in male Wistar rats.Naunyn-Schmiedeberg's archives of pharmacology · 2023Article
- Acute kidney injury due to bilateral malignant ureteral obstruction: Is there an optimal mode of drainage?World journal of nephrology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The response of the kidney and its recovery following unilateral ureteral obstruction (UUO) depend on several factors including the duration of obstruction, the species involved and the age of the individual. In neonates, there is compelling evidence to indicate that even short periods of reversible UUO might lead to long-term renal impairment. In adults, the glomerular filtration rate returns to baseline values soon after the release of short periods of UUO. Despite this return to normal, experimental data have demonstrated that short periods of reversible UUO could lead to long-term renal functional alterations including tubular atrophy, interstitial fibrosis and urinary albumin leakage in addition to alterations in pro-inflammatory and pro-fibrotic cytokines. The concentrating ability of the kidney and its response to stimuli such as renal nerve stimulation and physiological doses of angiotensin-II were also shown to be affected at least in the intermediate-term following UUO reversal. In humans, epidemiological studies have also demonstrated a clear association between long-term renal impairment and ureteral obstruction. However, in clinical studies, it is usually difficult to precisely determine the degree and the time of onset of ureteral obstruction and more studies are required in this field. In conclusion, the available experimental and clinical data indicate that even short periods of UUO can cause long-term renal dysfunction. These findings might have clinical implications related to the early intervention following acute onset of UUO and to the need for long-term monitoring of renal functions particularly in patients with underlying chronic renal disease.
Indexed as
Identifiers
35619661PMC9123473W4285741809What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.