Evidence mapPaperPMID 35620571Full record

SynthesisJournal of diabetes research2022

Systematic Review of Literature Examining Bacterial Urinary Tract Infections in Diabetes.

Santosh Paudel, Preeti P John, Seyedeh Leila Poorbaghi, Tara M Randis, Ritwij Kulkarni

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Journal of diabetes research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Carbapenem-resistantbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Molecular Characterization of High and Low VirulentInfection and drug resistance · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Santosh PaudelDepartment of Biology, University of Louisiana at Lafayette, Lafayette, LA, USA 70504.ORCID https://orcid.org/0000-0002-5266-391X
Preeti P JohnDepartment of Biology, University of Louisiana at Lafayette, Lafayette, LA, USA 70504.ORCID https://orcid.org/0000-0002-4942-2891
Seyedeh Leila PoorbaghiNew Iberia Research Center, University of Louisiana at Lafayette, Lafayette, LA, USA 70560.
Tara M RandisDepartment of Pediatrics, University of South Florida, Tampa, FL, USA 33620.ORCID https://orcid.org/0000-0003-0348-6766
Ritwij KulkarniDepartment of Biology, University of Louisiana at Lafayette, Lafayette, LA, USA 70504.ORCID https://orcid.org/0000-0002-9753-8899
University of Louisiana at Lafayette · USUniversity of South Florida · US

Funding

NIAID NIH HHS R21 AI165939
6 · The paper itself

Abstract

This systematic review addresses the central research question, "what is known from the published, peer-reviewed literature about the impact of diabetes on the risk of bacterial urinary tract infections (UTI)?" We examine the results from laboratory studies where researchers have successfully adapted mouse models of diabetes to study the pathophysiology of ascending UTI. These studies have identified molecular and cellular effectors shaping immune defenses against infection of the diabetic urinary tract. In addition, we present evidence from clinical studies that in addition to diabetes, female gender, increased age, and diabetes-associated hyperglycemia, glycosuria, and immune impairment are important risk factors which further increase the risk of UTI in diabetic individuals. Clinical studies also show that the uropathogenic genera causing UTI are largely similar between diabetic and nondiabetic individuals, although diabetes significantly increases risk of UTI by drug-resistant uropathogenic bacteria.

Indexed as

Bacterial InfectionsDiabetes MellitusUrinary Tract InfectionsAnimalsFemaleMice

Identifiers

PMID35620571
PMCPMC9130015
OpenAlexW4280505039

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.