Evidence map›Paper›PMID 35622158›Full record

ArticleCellular and molecular life sciences : CMLS2022

Misaligned feeding schedule elicits divergent circadian reorganizations in endo- and exocrine pancreas clocks.

Petra Honzlová, Zuzana Novosadová, Pavel Houdek, Martin Sládek, Alena Sumová

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Petra HonzlováLaboratory of Biological Rhythms, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220, Prague, Czech Republic.
Zuzana NovosadováLaboratory of Biological Rhythms, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220, Prague, Czech Republic.
Pavel HoudekLaboratory of Biological Rhythms, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220, Prague, Czech Republic.
Martin SládekLaboratory of Biological Rhythms, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220, Prague, Czech Republic.
Alena SumováLaboratory of Biological Rhythms, Institute of Physiology of the Czech Academy of Sciences, Videnska 1083, 14220, Prague, Czech Republic. alena.sumova@fgu.cas.cz.ORCID http://orcid.org/0000-0003-4126-5470
Czech Academy of Sciences · CZ

Funding

Ministerstvo Školství, Mládeže a Tělovýchovy LM2015062 Czech-BioImagingOPPK BrainView CZ.2.16/3.1.00/21544Research project RVO 67985823
6 · The paper itself

Abstract

Misaligned feeding may lead to pancreatic insufficiency, however, whether and how it affects circadian clock in the exocrine pancreas is not known. We exposed rats to a reversed restricted feeding regimen (rRF) for 10 or 20 days and analyzed locomotor activity, daily profiles of hormone levels (insulin, glucagon, and corticosterone) in plasma, and clock gene expression in the liver and endocrine and exocrine pancreas. In addition, we monitored responses of the exocrine pancreatic clock in organotypic explants of mPer2

Indexed as

Circadian ClocksPancreas, ExocrineAnimalsCircadian RhythmCorticosteroneGlucocorticoidsInsulinMiceRatsCorticosteroneGlucocorticoidsInsulinCircadian clockDexamethasoneInsulinMisaligned feedingmPer2Luc mousePancreas

Identifiers

PMID35622158
PMCPMC11072313
OpenAlexW4281749373

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.