Evidence map›Paper›PMID 35622727›Full record

ReviewVeterinary sciences2022

Bee Stressors from an Immunological Perspective and Strategies to Improve Bee Health.

Hesham R El-Seedi, Hanan R Ahmed, Aida A Abd El-Wahed, Aamer Saeed, Ahmed F Algethami, Nour F Attia, Zhiming Guo, Syed G Musharraf, Alfi Khatib, Sultan M Alsharif and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Veterinary sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
13.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 72 citations in OpenAlex.

  1. Ashwagandha Extract as a Promising Source of Immunology Support forAnimals : an open access journal from MDPI · 2026
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  18. Heavy Metal Concentrations of Beeswax (Apis mellifera L.) at Different Ages.Bulletin of environmental contamination and toxicology · 2023
    Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 8 countries.

Hesham R El-SeediPharmacognosy Group, Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Centre, P.O. Box 591, SE 751 24 Uppsala, Sweden.ORCID 0000-0002-2519-6690
Hanan R AhmedDepartment of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt.
Aida A Abd El-WahedDepartment of Bee Research, Plant Protection Research Institute, Agricultural Research Centre, Giza 12627, Egypt.ORCID 0000-0002-2200-3507
Aamer SaeedDepartment of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.
Ahmed F AlgethamiAl nahal al jwal Foundation Saudi Arabia, P.O. Box 617, Al Jumum, Makkah 21926, Saudi Arabia.
Nour F AttiaChemistry Division, National Institute of Standards, 136, Giza 12211, Egypt.ORCID 0000-0002-0713-1738
Zhiming GuoSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0001-6416-7457
Syed G MusharrafH.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
Alfi KhatibDepartment of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic Univetsity Malaysia, Kuantan 25200, Malaysia.ORCID 0000-0002-5480-0789
Sultan M AlsharifBiology Department, Faculty of Science, Taibah University, Al Madinah 887, Saudi Arabia.
Yahya Al NaggarZoology Department, Faculty of Science, Tanta University, Tanta 31527, Egypt.ORCID 0000-0002-8111-918X
Shaden A M KhalifaDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE 106 91 Stockholm, Sweden.
Kai WangInstitute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China.ORCID 0000-0003-0553-5293
Jiangsu University · CNAgricultural Research Center · EGAirlangga University · IDChinese Academy of Agricultural Sciences · CNMenoufia University · EGNational Institute of Standards · EGQuaid-i-Azam University · PKStockholm University · SETaibah University · SATanta University · EGUniversity of Karachi · PK

Funding

Swedish Research Council Vetenskapsrådet VR Grant 2016-05885
6 · The paper itself

Abstract

Honeybees are the most prevalent insect pollinator species; they pollinate a wide range of crops. Colony collapse disorder (CCD), which is caused by a variety of biotic and abiotic factors, incurs high economic/ecological loss. Despite extensive research to identify and study the various ecological stressors such as microbial infections, exposure to pesticides, loss of habitat, and improper beekeeping practices that are claimed to cause these declines, the deep understanding of the observed losses of these important insects is still missing. Honeybees have an innate immune system, which includes physical barriers and cellular and humeral responses to defend against pathogens and parasites. Exposure to various stressors may affect this system and the health of individual bees and colonies. This review summarizes and discusses the composition of the honeybee immune system and the consequences of exposure to stressors, individually or in combinations, on honeybee immune competence. In addition, we discuss the relationship between bee nutrition and immunity. Nutrition and phytochemicals were highlighted as the factors with a high impact on honeybee immunity.

Indexed as

agrochemicalsecological stressorshoneybeesimmunitynutritionsustainable beekeeping

Identifiers

PMID35622727
PMCPMC9146872
OpenAlexW4224316484

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.