Evidence map›Paper›PMID 35624430›Full record

SynthesisBMC ophthalmology2022

Correlation between the progression of diabetic retinopathy and inflammasome biomarkers in vitreous and serum - a systematic review.

Charisse Y J Kuo, Rinki Murphy, Ilva D Rupenthal, Odunayo O Mugisho

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Charisse Y J KuoBuchanan Ocular Therapeutics Unit, New Zealand National Eye Centre, Department of Ophthalmology, The University of Auckland, Auckland, 1023, New Zealand.
Rinki MurphyDepartment of Medicine, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, 1023, New Zealand.
Ilva D RupenthalBuchanan Ocular Therapeutics Unit, New Zealand National Eye Centre, Department of Ophthalmology, The University of Auckland, Auckland, 1023, New Zealand.
Odunayo O MugishoBuchanan Ocular Therapeutics Unit, New Zealand National Eye Centre, Department of Ophthalmology, The University of Auckland, Auckland, 1023, New Zealand. lola.mugisho@auckland.ac.nz.
University of Auckland · NZ

Funding

Neurological Foundation of New Zealand 2001 FFE
6 · The paper itself

Abstract

Activation of the NOD-like receptor protein 3 (NLRP3) inflammasome pathway has been implicated in Diabetic retinopathy (DR) pathogenesis, but its impact on DR development and progression remains unclear. Therefore, the primary aim of this systematic literature review was to determine the role of the inflammasome in DR development. Furthermore, the secondary aim was to determine whether systemic inflammasome activity can be used to predict DR progression. Studies measuring vitreous and/or serum inflammasome biomarkers in DR patients with Type 2 Diabetes Mellitus (T2DM) were searched systematically using online databases EMBASE, PubMed and Web of Science with the last search conducted on 29

Indexed as

Diabetes Mellitus, Type 2Diabetic RetinopathyBiomarkersHumansInflammasomesBiomarkersInflammasomesBiomarkersCytokinesDiabetic retinopathyInflammasomeSerumVitreous

Identifiers

PMID35624430
PMCPMC9145105
OpenAlexW4281698401

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.