Evidence map›Paper›PMID 35626641›Full record

ReviewCells2022

Deconstructing Sox2 Function in Brain Development and Disease.

Sara Mercurio, Linda Serra, Miriam Pagin, Silvia K Nicolis

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 49 citations in OpenAlex.

  1. Iron dysregulation in the central nervous system: implications for autism spectrum disorder.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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  15. Incubator-Free Organoid Culture in a Sealed Recirculatory System.bioRxiv : the preprint server for biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sara MercurioDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.
Linda SerraDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.
Miriam PaginDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0003-2160-3313
Silvia K NicolisDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0003-0378-3808
University of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SOX2 is a transcription factor conserved throughout vertebrate evolution, whose expression marks the central nervous system from the earliest developmental stages. In humans,

Indexed as

Neural Stem CellsNeurogliaAnimalsBrainCentral Nervous SystemHumansMiceSOXB1 Transcription FactorsTranscription FactorsSOX2 protein, humanSox2 protein, mouseSOXB1 Transcription FactorsTranscription Factorsbraindevelopmentglianeural stem cellsneuronsSox2transcription factor

Identifiers

PMID35626641
PMCPMC9139651
OpenAlexW4280542794

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.