Evidence map›Paper›PMID 35627129›Full record

ArticleGenes2022

The Role of Functional Polymorphisms in the Extracellular Matrix Modulation-Related Genes on Dupuytren's Contracture.

Gediminas Samulenas, Ruta Insodaite, Edita Kunceviciene, Roberta Poceviciute, Lorena Masionyte, Urte Zitkeviciute, Loreta Pilipaityte, Alina Smalinskiene

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Gediminas SamulenasDepartment of Plastic and Reconstructive Surgery, Lithuanian University of Health Sciences, LT 50009 Kaunas, Lithuania.
Ruta InsodaiteInstitute of Biology Systems and Genetics Research, Lithuanian University of Health Sciences, LT 50103 Kaunas, Lithuania.
Edita KuncevicieneInstitute of Biology Systems and Genetics Research, Lithuanian University of Health Sciences, LT 50103 Kaunas, Lithuania.
Roberta PoceviciuteInstitute of Biology Systems and Genetics Research, Lithuanian University of Health Sciences, LT 50103 Kaunas, Lithuania.
Lorena MasionyteInstitute of Biology Systems and Genetics Research, Lithuanian University of Health Sciences, LT 50103 Kaunas, Lithuania.
Urte ZitkeviciuteFaculty of Medicine, Lithuanian University of Health Sciences, LT 44307 Kaunas, Lithuania.
Loreta PilipaityteDepartment of Plastic and Reconstructive Surgery, Lithuanian University of Health Sciences, LT 50009 Kaunas, Lithuania.
Alina SmalinskieneInstitute of Biology Systems and Genetics Research, Lithuanian University of Health Sciences, LT 50103 Kaunas, Lithuania.
Lithuanian University of Health Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: genetic variations, localized in the functional regions of the extracellular matrix (ECM) modulation-related genes, may alter the transcription process and impact the Dupuytren's contracture (DC). The present study investigated the association of single nucleotide polymorphisms (SNPs), localized in the functional regions of the

Indexed as

Dupuytren ContractureMatrix Metalloproteinase 14SulfotransferasesCarbohydrate SulfotransferasesExtracellular MatrixHumansMatrix Metalloproteinase 8Polymorphism, Single NucleotideCarbohydrate SulfotransferasesMatrix Metalloproteinase 14Matrix Metalloproteinase 8MMP14 protein, humanMMP8 protein, humanSulfotransferasesCHST6Dupuytren’s contractureextracellular matrixMMP14MMP8single-nucleotide polymorphism

Identifiers

PMID35627129
PMCPMC9141853
OpenAlexW4282943788

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.