Evidence map›Paper›PMID 35627222›Full record

ArticleGenes2022

Feature Fusion and Detection in Alzheimer's Disease Using a Novel Genetic Multi-Kernel SVM Based on MRI Imaging and Gene Data.

Xianglian Meng, Qingpeng Wei, Li Meng, Junlong Liu, Yue Wu, Wenjie Liu

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Xianglian MengSchool of Computer Information and Engineering, Changzhou Institute of Technology, Changzhou 213032, China.ORCID 0000-0001-5150-6456
Qingpeng WeiSchool of Computer Information and Engineering, Changzhou Institute of Technology, Changzhou 213032, China.
Li MengSchool of Physics, Engineering and Computer Science, University of Hertfordshire, Hatfield AL10 9AB, UK.
Junlong LiuSchool of Computer Information and Engineering, Changzhou Institute of Technology, Changzhou 213032, China.
Yue WuSchool of Computer Information and Engineering, Changzhou Institute of Technology, Changzhou 213032, China.
Wenjie LiuSchool of Computer Information and Engineering, Changzhou Institute of Technology, Changzhou 213032, China.ORCID 0000-0003-3220-5820
Changzhou Institute of Technology · CNUniversity of Hertfordshire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Voxel-based morphometry provides an opportunity to study Alzheimer's disease (AD) at a subtle level. Therefore, identifying the important brain voxels that can classify AD, early mild cognitive impairment (EMCI) and healthy control (HC) and studying the role of these voxels in AD will be crucial to improve our understanding of the neurobiological mechanism of AD. Combining magnetic resonance imaging (MRI) imaging and gene information, we proposed a novel feature construction method and a novel genetic multi-kernel support vector machine (SVM) method to mine important features for AD detection. Specifically, to amplify the differences among AD, EMCI and HC groups, we used the eigenvalues of the top 24 Single Nucleotide Polymorphisms (SNPs) in a

Indexed as

Alzheimer DiseaseCognitive DysfunctionBrainHumansMagnetic Resonance ImagingSupport Vector MachineAlzheimer’s diseaseeigenvaluegenegenetic multi-kernel SVMMRI imagingsignificant feature

Identifiers

PMID35627222
PMCPMC9140721
OpenAlexW4229332226

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.