Evidence map›Paper›PMID 35628108›Full record

ArticleInternational journal of molecular sciences2022

Solvation, Cancer Cell Photoinactivation and the Interaction of Chlorin Photosensitizers with a Potential Passive Carrier Non-Ionic Surfactant Tween 80.

Andrey V Kustov, Philipp K Morshnev, Natal'ya V Kukushkina, Nataliya L Smirnova, Dmitry B Berezin, Dmitry R Karimov, Olga V Shukhto, Tatyana V Kustova, Dmitry V Belykh, Marina V Mal'shakova and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Natural Chlorin eACS omega · 2026
    Article
  2. Review
  3. Review
  4. Photosensitizing effects and physicochemical properties of chlorophyll a derivatives with hydrophilic oligoethylene glycol fragments at the macrocycle periphery.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Article
  5. Review
  6. Article
  7. Amino Acid Derivatives of Chlorin-eMolecules (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Andrey V KustovUnited Physicochemical Centre of Solutions, G.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russia.
Philipp K MorshnevUnited Physicochemical Centre of Solutions, G.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russia.ORCID 0000-0003-2119-605X
Natal'ya V KukushkinaUnited Physicochemical Centre of Solutions, G.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russia.
Nataliya L SmirnovaUnited Physicochemical Centre of Solutions, G.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russia.
Dmitry B BerezinInstitute of Macroheterocyclic Compounds, Ivanovo State University of Chemistry and Technology (ISUCT), 153012 Ivanovo, Russia.ORCID 0000-0001-5814-9105
Dmitry R KarimovInstitute of Macroheterocyclic Compounds, Ivanovo State University of Chemistry and Technology (ISUCT), 153012 Ivanovo, Russia.
Olga V ShukhtoInstitute of Macroheterocyclic Compounds, Ivanovo State University of Chemistry and Technology (ISUCT), 153012 Ivanovo, Russia.
Tatyana V KustovaInstitute of Macroheterocyclic Compounds, Ivanovo State University of Chemistry and Technology (ISUCT), 153012 Ivanovo, Russia.
Dmitry V BelykhInstitute of Chemistry of the Komi Science Centre of the Ural Branch of Russian Academy of Sciences (ICKSC UB RAS), 167000 Syktyvkar, Russia.
Marina V Mal'shakovaInstitute of Chemistry of the Komi Science Centre of the Ural Branch of Russian Academy of Sciences (ICKSC UB RAS), 167000 Syktyvkar, Russia.
Vladimir P ZorinDepartment of Biophysics, Belarussian State University (BSU), 220030 Minsk, Belarus.
Tatyana E ZorinaDepartment of Biophysics, Belarussian State University (BSU), 220030 Minsk, Belarus.
Ivanovo State University of Chemistry and Technology · RUInstitute of Solution Chemistry · RUBelarusian State University · BYRussian Academy of Sciences · RU

Funding

Russian Science Foundation 21-13-00398
6 · The paper itself

Abstract

Cancer and drug-resistant superinfections are common and serious problems afflicting millions worldwide. Photodynamic therapy (PDT) is a successful and clinically approved modality used for the management of many neoplastic and nonmalignant diseases. The combination of the light-activated molecules, so-called photosensitizers (PSs), with an appropriate carrier, is proved to enhance PDT efficacy both in vitro and in vivo. In this paper, we focus on the solvation of several potential chlorin PSs in the 1-octanol/phosphate saline buffer biphasic system, their interaction with non-ionic surfactant Tween 80 and photoinactivation of cancer cells. The chlorin conjugates containing

Indexed as

NeoplasmsPulmonary SurfactantsArginineExcipientsGalactoseHumansLipidsMicellesPhotosensitizing AgentsPolysorbatesPorphyrinsSurface-Active AgentsArgininechlorinExcipientsGalactoseLipidsMicellesPhotosensitizing AgentsPolysorbatesPorphyrinsPulmonary SurfactantsSurface-Active Agents1-octanol/phosphate saline buffer partitionchlorin photosensitizersinteraction with Tween 80photodynamic therapyphotoinactivationsinglet oxygen generationsolvation

Identifiers

PMID35628108
PMCPMC9140634
OpenAlexW4229442229

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.