Evidence map›Paper›PMID 35628299›Full record

ArticleInternational journal of molecular sciences2022

Nitric Oxide Mobilizes Intracellular Zn

Chien-Wei Chen, Luen-Kui Chen, Tai-Ying Huang, De-Ming Yang, Shui-Yu Liu, Pei-Jiun Tsai, Tien-Hua Chen, Heng-Fu Lin, Chi-Chang Juan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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  7. Zinc homeostasis and redox alterations in obesity.Frontiers in endocrinology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Chien-Wei ChenCollege of Human Development and Health, National Taipei University of Nursing and Health Sciences, Taipei 112303, Taiwan.
Luen-Kui ChenInstitute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Tai-Ying HuangInstitute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
De-Ming YangInstitute of Biophotonics, College of Biomedical Science and Engineering, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0002-6923-4855
Shui-Yu LiuInstitute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Pei-Jiun TsaiInstitute of Anatomy and Cell Biology, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Tien-Hua ChenInstitute of Anatomy and Cell Biology, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Heng-Fu LinDivision of Trauma, Department of Surgery, Far-Eastern Memorial Hospital, New Taipei City 220216, Taiwan.
Chi-Chang JuanInstitute of Physiology, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0001-5935-6675
National Yang Ming Chiao Tung University · TWFar Eastern Memorial Hospital · TWNational Taipei University of Nursing and Health Science · TW

Funding

FEMH-NYCU Joint Research Program FEMH-NYCU 106DN06 and 108DN06Ministry of Science and Technology NSC 98-2341-B-010-005-MY3National Taipei University of Nursing and Health Sciences 109ntunhs‑NT‑04
6 · The paper itself

Abstract

Plasma and tissue zinc ion levels are associated with the development of obesity. Previous studies have suggested that zinc ions may regulate adipocyte metabolism and that nitric oxide (NO) plays a pivotal role in the regulation of adipocyte physiology. Our previous study showed that chronic NO deficiency causes a significant decrease in adipose tissue mass in rats. Studies also suggested that zinc ions play an important modulatory role in regulating NO function. This study aims to explore the role of zinc ions in NO-regulated adipocyte differentiation. We hypothesized that NO could increase intracellular Zn

Indexed as

AdipocytesCyclic GMPCyclic GMP-Dependent Protein KinasesGuanylate CyclaseNitric OxideZincAnimalsRatsSignal TransductionCyclic GMPCyclic GMP-Dependent Protein KinasesGuanylate CyclaseNitric OxideZincadipocytedifferentiationguanylyl cyclasenitric oxideobesityprotein kinase Gzinc

Identifiers

PMID35628299
PMCPMC9143299
OpenAlexW4280602143

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.