Evidence map›Paper›PMID 35628354›Full record

ReviewInternational journal of molecular sciences2022

MicroRNAs: Important Regulatory Molecules in Acute Lung Injury/Acute Respiratory Distress Syndrome.

Qianying Lu, Sifan Yu, Xiangyan Meng, Mingyu Shi, Siyu Huang, Junfeng Li, Jianfeng Zhang, Yangfan Liang, Mengjun Ji, Yanmei Zhao and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
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  10. Effects of remote ischemic preconditioning and/or erythropoietin on lung injury induced by skeletal ischemia reperfusion: role of the NLRP3 inflammasome.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Qianying LuInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.
Sifan YuInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.
Xiangyan MengInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.
Mingyu ShiInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.
Siyu HuangInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.
Junfeng LiInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.
Jianfeng ZhangInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.
Yangfan LiangInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.
Mengjun JiInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.
Yanmei ZhaoInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.ORCID 0000-0002-8572-6470
Haojun FanInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin 300072, China.
Tianjin University · CN

Funding

Open Scientific Research Program of Military Logistics BLB19J006Open Scientific Research Program of Military Logistics BLB20J009
6 · The paper itself

Abstract

Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is an overactivated inflammatory response caused by direct or indirect injuries that destroy lung parenchymal cells and dramatically reduce lung function. Although some research progress has been made in recent years, the pathogenesis of ALI/ARDS remains unclear due to its heterogeneity and etiology. MicroRNAs (miRNAs), a type of small noncoding RNA, play a vital role in various diseases. In ALI/ARDS, miRNAs can regulate inflammatory and immune responses by targeting specific molecules. Regulation of miRNA expression can reduce damage and promote the recovery of ALI/ARDS. Consequently, miRNAs are considered as potential diagnostic indicators and therapeutic targets of ALI/ARDS. Given that inflammation plays an important role in the pathogenesis of ALI/ARDS, we review the miRNAs involved in the inflammatory process of ALI/ARDS to provide new ideas for the pathogenesis, clinical diagnosis, and treatment of ALI/ARDS.

Indexed as

Acute Lung InjuryMicroRNAsRespiratory Distress SyndromeHumansInflammationLungMicroRNAsacute lung injuryacute respiratory distress syndromebiomarkerinflammationMicroRNAs

Identifiers

PMID35628354
PMCPMC9142048
OpenAlexW4280579989

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.