Evidence map›Paper›PMID 35629941›Full record

ArticleMetabolites2022

Metabolite Signature in the Carriers of Pathogenic Genetic Variants for Cardiomyopathy: A Population-Based METSIM Study.

Rowmika Ravi, Lilian Fernandes Silva, Jagadish Vangipurapu, Maleeha Maria, Joose Raivo, Seppo Helisalmi, Markku Laakso

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rowmika RaviInstitute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.ORCID 0000-0001-7994-8547
Lilian Fernandes SilvaInstitute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.ORCID 0000-0003-0225-842X
Jagadish VangipurapuInstitute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.
Maleeha MariaA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70210 Kuopio, Finland.
Joose RaivoInstitute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.
Seppo HelisalmiInstitute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.
Markku LaaksoInstitute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.

Funding

Genetic epidemiology of rare and regulatory variants for metabolic traitsR01DK093757 · UNIV OF NORTH CAROLINA CHAPEL HILL · 2025 to 2025
$562k
Academy of Finland 321428Centre of Excellence of Cardiovascular and Metabolic DiseasesFinnish Foundation for Cardiovascular ResearchKuopio University HospitalNIDDK NIH HHS R01 DK093757NIDDK NIH HHS U01 DK062370NIH HHS 2U01DK062370-15NIH HHS 5R01DK093757-10Sigrid Jusélius Foundation
6 · The paper itself

Abstract

Hypertrophic (HCM) and dilated (DCM) cardiomyopathies are among the leading causes of sudden cardiac death. We identified 38 pathogenic or likely pathogenic variant carriers for HCM in three sarcomere genes (

Indexed as

dilated cardiomyopathyhypertrophic cardiomyopathymetabolitesmetabolomics

Identifiers

PMID35629941
PMCPMC9143630

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.