Evidence map›Paper›PMID 35631064›Full record

ArticlePathogens (Basel, Switzerland)2022

Antibiotic Resistance in Non-Typhoidal

Minori Takaichi, Kayo Osawa, Ryohei Nomoto, Noriko Nakanishi, Masanori Kameoka, Makiko Miura, Katsumi Shigemura, Shohiro Kinoshita, Koichi Kitagawa, Atsushi Uda and 8 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. A spotlight on multidrug-resistantFrontiers in microbiology · 2026
    Review
  4. Article
  5. Article
  6. Antibiogram profile ofVeterinary world · 2025
    Article
  7. Article
  8. Whole-Genome Sequencing Analysis of Non-TyphoidalAntibiotics (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 2 countries.

Minori TakaichiDepartment of Public Health, Kobe University Graduate School of Health Sciences, Kobe 654-0142, Japan.
Kayo OsawaDepartment of Medical Technology, Kobe Tokiwa University, Kobe 653-0838, Japan.ORCID 0000-0002-4787-4333
Ryohei NomotoDepartment of Infectious Diseases, Kobe Institute of Health, Kobe 650-0046, Japan.ORCID 0000-0002-5024-9520
Noriko NakanishiDepartment of Infectious Diseases, Kobe Institute of Health, Kobe 650-0046, Japan.ORCID 0000-0002-3088-1254
Masanori KameokaDepartment of Public Health, Kobe University Graduate School of Health Sciences, Kobe 654-0142, Japan.ORCID 0000-0001-5525-9915
Makiko MiuraDepartment of Medical Technology, Kobe Tokiwa University, Kobe 653-0838, Japan.
Katsumi ShigemuraDepartment of Public Health, Kobe University Graduate School of Health Sciences, Kobe 654-0142, Japan.
Shohiro KinoshitaDivision of Advanced Medical Science, Kobe University Graduate School of Science, Technology and Innovation, Kobe 650-0017, Japan.
Koichi KitagawaDivision of Advanced Medical Science, Kobe University Graduate School of Science, Technology and Innovation, Kobe 650-0017, Japan.
Atsushi UdaDepartment of Infection Control and Prevention, Kobe University Hospital, Kobe 650-0017, Japan.
Takayuki MiyaraDepartment of Infection Control and Prevention, Kobe University Hospital, Kobe 650-0017, Japan.
Ni Made MertaniasihDepartment of Microbiology, Faculty of Medicine, Airlangga University, Surabaya 60132, Indonesia.
Usman HadiDepartment of Microbiology, Faculty of Medicine, Airlangga University, Surabaya 60132, Indonesia.
Dadik RaharjoInstitute of Tropical Disease, Airlangga University, Surabaya 60286, Indonesia.
Ratna YulistianiDepartment of Food Technology, Faculty of Engineering, Universitas Pembangunan Nasional Veteran Jawa Timur, Surabaya 60294, Indonesia.
Masato FujisawaDivision of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Kuntaman KuntamanInstitute of Tropical Disease, Airlangga University, Surabaya 60286, Indonesia.
Toshiro ShirakawaDivision of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Kobe University · JPAirlangga University · IDKobe Tokiwa University · JPKobe University Hospital · JPUniversity of Pembangunan Nasional Veteran Jawa Timur · ID

Funding

Japan Society for the Promotion of Science (JSPS) KAKENHI 21K10423the Japan Agency for Medical Research and Development (AMED) JP18fk0108019the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) from the Min-istry of Education, Culture, Sport, Science and Technology in Japan 18fm0108004h0004the Tahir Professorship of Airlangga University 1149/UN3/2018
6 · The paper itself

Abstract

The increase in antibiotic resistance in non-typhoidal Salmonella enterica (NTS) has been confirmed in Indonesia by this study. We confirmed the virulence genes and antimicrobial susceptibilities of clinical NTS (n = 50) isolated from chicken meat in Indonesia and also detected antimicrobial resistance genes. Of 50 strains, 30 (60%) were non-susceptible to nalidixic acid (NA) and all of them had amino acid mutations in gyrA. Among 27 tetracycline (TC) non-susceptible strains, 22 (81.5%) had tetA and/or tetB. The non-susceptibility rates to ampicillin, gentamicin or kanamycin were lower than that of NA or TC, but the prevalence of blaTEM or aadA was high. Non-susceptible strains showed a high prevalence of virulence genes compared with the susceptible strains (tcfA, p = 0.014; cdtB, p < 0.001; sfbA, p < 0.001; fimA, p = 0.002). S. Schwarzengrund was the most prevalent serotype (23 strains, 46%) and the most frequently detected as multi-antimicrobial resistant. The prevalence of virulence genes in S. Schwarzengrund was significantly higher than other serotypes in hlyE (p = 0.011) and phoP/Q (p = 0.011) in addition to the genes above. In conclusion, NTS strains isolated from Indonesian chicken had a high resistance to antibiotics and many virulence factors. In particular, S. Schwarzengrund strains were most frequently detected as multi-antimicrobial resistant and had a high prevalence of virulence genes.

Indexed as

antimicrobial resistancechickenIndonesianon-typhoidal Salmonella enterica (NTS)virulence factors

Identifiers

PMID35631064
PMCPMC9143091
OpenAlexW4229078656

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.