Evidence mapPaperPMID 35631211Full record

ReviewNutrients2022

Current Hydration Habits: The Disregarded Factor for the Development of Renal and Cardiometabolic Diseases.

Richard J Johnson, Fernando E García-Arroyo, Guillermo Gonzaga-Sánchez, Kevin A Vélez-Orozco, Yamnia Quetzal Álvarez-Álvarez, Omar Emiliano Aparicio-Trejo, Edilia Tapia, Horacio Osorio-Alonso, Ana Andrés-Hernando, Takahiko Nakagawa and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Richard J JohnsonDivision of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
Fernando E García-ArroyoDepartment Cardio-Renal Physiopathology, INC Ignacio Chávez, Mexico City 14080, Mexico.
Guillermo Gonzaga-SánchezDepartment Cardio-Renal Physiopathology, INC Ignacio Chávez, Mexico City 14080, Mexico.
Kevin A Vélez-OrozcoDepartment Cardio-Renal Physiopathology, INC Ignacio Chávez, Mexico City 14080, Mexico.
Yamnia Quetzal Álvarez-ÁlvarezDepartment Cardio-Renal Physiopathology, INC Ignacio Chávez, Mexico City 14080, Mexico.
Omar Emiliano Aparicio-TrejoDepartment Cardio-Renal Physiopathology, INC Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0000-0002-7701-4537
Edilia TapiaDepartment Cardio-Renal Physiopathology, INC Ignacio Chávez, Mexico City 14080, Mexico.
Horacio Osorio-AlonsoDepartment Cardio-Renal Physiopathology, INC Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0000-0002-9238-4202
Ana Andrés-HernandoDivision of Nephrology and Hypertension, Oregon Health Sciences University, Portland, OR 97239, USA.
Takahiko NakagawaDepartment of Nephrology, Rakuwakai Otowa Hospital, Kyoto 607-8062, Japan.
Masanari KuwabaraIntensive Care Unit, Toranomon Hospital, Tokyo 105-8470, Japan.ORCID 0000-0002-6601-4347
Mehmet KanbayDivision of Nephrology, Department of Internal Medicine, Koc University School of Medicine, Istanbul 34010, Turkey.ORCID 0000-0002-1297-0675
Miguel A LanaspaDivision of Nephrology and Hypertension, Oregon Health Sciences University, Portland, OR 97239, USA.
Laura Gabriela Sánchez-LozadaDepartment Cardio-Renal Physiopathology, INC Ignacio Chávez, Mexico City 14080, Mexico.
Instituto Nacional de Cardiología · MXOregon Health & Science University · USKoç University · TRRakuwakai Otowa Hospital · JPToranomon Hospital · JPUniversity of Colorado Anschutz Medical Campus · US

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · UNIVERSITY OF COLORADO DENVER · 1995 to 2025
$7.7M
Silica Nephropathy and Chronic Kidney Disease of Unknown EtiologyR01DK125351 · UNIVERSITY OF COLORADO DENVER · 2025 to 2025
$700k
NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R01 DK108859NIDDK NIH HHS R01 DK121496NIDDK NIH HHS R01 DK125351
6 · The paper itself

Abstract

Improper hydration habits are commonly disregarded as a risk factor for the development of chronic diseases. Consuming an intake of water below recommendations (underhydration) in addition to the substitution of sugar-sweetened beverages (SSB) for water are habits deeply ingrained in several countries. This behavior is due to voluntary and involuntary dehydration; and because young children are exposed to SSB, the preference for a sweet taste is profoundly implanted in the brain. Underhydration and SSB intake lead to mild hyperosmolarity, which stimulates biologic processes, such as the stimulation of vasopressin and the polyol-fructose pathway, which restore osmolarity to normal but at the expense of the continued activation of these biological systems. Unfortunately, chronic activation of the vasopressin and polyol-fructose pathways has been shown to mediate many diseases, such as obesity, diabetes, metabolic syndrome, chronic kidney disease, and cardiovascular disease. It is therefore urgent that we encourage educational and promotional campaigns that promote the evaluation of personal hydration status, a greater intake of potable water, and a reduction or complete halting of the drinking of SSB.

Indexed as

Cardiovascular DiseasesDrinking WaterBeveragesChildChild, PreschoolFructoseHabitsHumansDrinking WaterFructosechronic kidney diseasemetabolic syndromeobesityunderhydrationwater intake

Identifiers

PMID35631211
PMCPMC9145744
OpenAlexW4280647237

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.