Evidence map›Paper›PMID 35631536›Full record

ArticlePharmaceutics2022

3,6'- and 1,6'-Dithiopomalidomide Mitigate Ischemic Stroke in Rats and Blunt Inflammation.

Yan-Rou Tsai, Dong Seok Kim, Shih-Chang Hsueh, Kai-Yun Chen, John Chung-Che Wu, Jia-Yi Wang, Yi-Syue Tsou, Inho Hwang, Yukyung Kim, Dayeon Gil and 9 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 3 countries.

Yan-Rou TsaiNeuroscience Research Center, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-3879-6177
Dong Seok KimAevisbio Inc., Gaithersburg, MD 20878, USA.
Shih-Chang HsuehDrug Design & Development Section, Translational Gerontology Branch, Intramural Research Program National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Kai-Yun ChenNeuroscience Research Center, Taipei Medical University, Taipei 110, Taiwan.
John Chung-Che WuNeuroscience Research Center, Taipei Medical University, Taipei 110, Taiwan.
Jia-Yi WangNeuroscience Research Center, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-9106-3351
Yi-Syue TsouDepartment of Neurosurgery, Taipei Medical University Hospital, Taipei Medical University, Taipei 110, Taiwan.
Inho HwangAevis Bio Inc., Daejeon 34141, Korea.ORCID 0000-0003-2039-3895
Yukyung KimAevis Bio Inc., Daejeon 34141, Korea.
Dayeon GilAevis Bio Inc., Daejeon 34141, Korea.
Eui Jung JoAevis Bio Inc., Daejeon 34141, Korea.ORCID 0000-0003-1131-2723
Baek-Soo HanResearch Center for Biodefence, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Korea.
David TweedieDrug Design & Development Section, Translational Gerontology Branch, Intramural Research Program National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Daniela LeccaDrug Design & Development Section, Translational Gerontology Branch, Intramural Research Program National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Michael T ScerbaDrug Design & Development Section, Translational Gerontology Branch, Intramural Research Program National Institute on Aging, NIH, Baltimore, MD 21224, USA.
Warren R SelmanDepartment of Neurological Surgery, Case Western Reserve University, Cleveland, OH 44106, USA.
Barry J HofferDepartment of Neurological Surgery, Case Western Reserve University, Cleveland, OH 44106, USA.
Nigel H GreigDrug Design & Development Section, Translational Gerontology Branch, Intramural Research Program National Institute on Aging, NIH, Baltimore, MD 21224, USA.ORCID 0000-0002-3032-1468
Yung-Hsiao ChiangNeuroscience Research Center, Taipei Medical University, Taipei 110, Taiwan.
National Institute on Aging · USTaipei Medical University Hospital · TWKorea Research Institute of Bioscience and Biotechnology · KRNeurological Surgery · USTaipei Medical University · TWUniversity Hospitals of Cleveland · US

Funding

Eating Behaviors in Homebound Older AdultsK01AG000994 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LOCHER, JULIE L · 2001 to 2005
$503k
NIA NIH HHS K01 AG000994
6 · The paper itself

Abstract

(

Indexed as

1,6′-dithiopomalidomide3,6′-dithiopomalidomidecereblonimmunomodulatory imide drugs (IMiDs)inflammationischemic strokepomalidomideTNF-α

Identifiers

PMID35631536
PMCPMC9146426
OpenAlexW4225007049

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.