Evidence map›Paper›PMID 35631580›Full record

ArticlePharmaceutics2022

Laser Synthesized Core-Satellite Fe-Au Nanoparticles for Multimodal In Vivo Imaging and In Vitro Photothermal Therapy.

Olga Yu Griaznova, Iaroslav B Belyaev, Anna S Sogomonyan, Ivan V Zelepukin, Gleb V Tikhonowski, Anton A Popov, Aleksei S Komlev, Petr I Nikitin, Dmitry A Gorin, Andrei V Kabashin and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Long-Term Biodistribution of FeInternational journal of molecular sciences · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. CT and MRI Imaging of Theranostic Bimodal FeInternational journal of molecular sciences · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Olga Yu GriaznovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.ORCID 0000-0002-6180-7444
Iaroslav B BelyaevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Anna S SogomonyanShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Ivan V ZelepukinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.ORCID 0000-0003-0209-2116
Gleb V TikhonowskiInstitute for Physics and Engineering in Biomedicine (PhysBio), National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow 115409, Russia.ORCID 0000-0003-4998-1631
Anton A PopovInstitute for Physics and Engineering in Biomedicine (PhysBio), National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow 115409, Russia.
Aleksei S KomlevFaculty of Physics, M.V. Lomonosov Moscow State University, Moscow 119991, Russia.ORCID 0000-0003-4319-3781
Petr I NikitinInstitute for Physics and Engineering in Biomedicine (PhysBio), National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow 115409, Russia.ORCID 0000-0003-1573-5512
Dmitry A GorinCenter for Photonic Science and Engineering, Skolkovo Institute of Science and Technology, 3 Nobel Str, Moscow 121205, Russia.
Andrei V KabashinInstitute for Physics and Engineering in Biomedicine (PhysBio), National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow 115409, Russia.
Sergey M DeyevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Institute of Bioorganic Chemistry · RUNational Research Nuclear University MEPhI · RUSkolkovo Institute of Science and Technology · RUCentre National de la Recherche Scientifique · FRLomonosov Moscow State University · RUProkhorov General Physics Institute · RU

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2020-773
6 · The paper itself

Abstract

Hybrid multimodal nanoparticles, applicable simultaneously to the noninvasive imaging and therapeutic treatment, are highly demanded for clinical use. Here, Fe-Au core-satellite nanoparticles prepared by the method of pulsed laser ablation in liquids were evaluated as dual magnetic resonance imaging (MRI) and computed tomography (CT) contrast agents and as sensitizers for laser-induced hyperthermia of cancer cells. The biocompatibility of Fe-Au nanoparticles was improved by coating with polyacrylic acid, which provided excellent colloidal stability of nanoparticles with highly negative ζ-potential in water (-38 ± 7 mV) and retained hydrodynamic size (88 ± 20 nm) in a physiological environment. The ferromagnetic iron cores offered great contrast in MRI images with r

Indexed as

CTiron-gold nanoparticlesMRImultimodal imagingpharmacokineticsphotothermal therapypulsed laser ablation in liquids

Identifiers

PMID35631580
PMCPMC9144942
OpenAlexW4229003964

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.