Evidence map›Paper›PMID 35631618›Full record

ArticlePharmaceutics2022

Compounded Nonsterile Preparations and FDA-Approved Commercially Available Liquid Products for Children: A North American Update.

Richard H Parrish, Lisa D Ashworth, Raimar Löbenberg, Sandra Benavides, Jeffrey J Cies, Robert B MacArthur

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Engineering stable Amlodipine suspensions for flexible compounding at King Khaled University Hospital.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2025
    Article
  3. The Bioavailability of CHF6563, an Ethanol-Free, Sublingual Neonatal Buprenorphine Formulation: A Bridging Study Conducted in Adults.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Richard H ParrishDepartment of Biomedical Sciences, Mercer University School of Medicine, Columbus, GA 31902, USA.ORCID 0000-0002-5324-9139
Lisa D AshworthDepartment of Pharmacy Services, Children's Health System of Texas, Dallas, TX 75235, USA.
Raimar LöbenbergFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB T6G 2R3, Canada.ORCID 0000-0002-0919-0213
Sandra BenavidesSchool of Pharmacy, Philadelphia College of Osteopathic Medicine, Suwanee, GA 30024, USA.
Jeffrey J CiesDepartment of Pediatrics, Drexel University College of Medicine, Philadelphia, PA 19129, USA.
Robert B MacArthurDepartment of Pharmacy Services, Rockefeller University Hospital, New York, NY 10065, USA.
Mercer University · USPhiladelphia College of Osteopathic Medicine · USRockefeller University Hospital · USSt. Christopher's Hospital for Children · USUniversity of Alberta · CA

Funding

Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational SuccessUL1TR001866 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY, KRUEGER, JAMES G · 2016 to 2025
$40.6M
NCATS NIH HHS UL1 TR001866
6 · The paper itself

Abstract

The purpose of this work was to evaluate the suitability of recent US Food and Drug Administration (US-FDA)-approved and marketed oral liquid, powder, or granule products for children in North America, to identify the next group of Active Pharmaceutical Ingredients (APIs) that have high potential for development as commercially available FDA-approved finished liquid dosage forms, and to propose lists of compounded nonsterile preparations (CNSPs) that should be developed as commercially available FDA-approved finished liquid dosage forms, as well as those that pharmacists should continue to compound extemporaneously. Through this identification and categorization process, the pharmaceutical industry, government, and professionals are encouraged to continue to work together to improve the likelihood that patients will receive high-quality standardized extemporaneously compounded CNSPs and US-FDA-approved products.

Indexed as

active pharmaceutical ingredientcompounded drugcompoundingextemporaneous formulationmanufactured materialmedicationmonographpediatricreference standards

Identifiers

PMID35631618
PMCPMC9144535
OpenAlexW4280547185

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.