Evidence map›Paper›PMID 35632686›Full record

ArticleViruses2022

Treatment Response and Drug Resistance Profiling of Genotype 6 of Hepatitis C Virus in HCV/HIV Co-Infected Patients: A Pilot Study from INDIA.

Ekta Gupta, Jasmine Samal, Amit Pandey, Gaurav Singh, Hajra A S Gupta, Reshu Agarwal, Manoj Kumar Sharma

Abstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ekta GuptaDepartment of Clinical Virology, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
Jasmine SamalDepartment of Clinical Virology, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
Amit PandeyDepartment of Clinical Virology, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
Gaurav SinghDepartment of Clinical Virology, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
Hajra A S GuptaDepartment of Innate Immunity, ICMR-National Institute for Research in Reproductive and Child Health, Mumbai 400012, India.
Reshu AgarwalDepartment of Clinical Virology, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
Manoj Kumar SharmaDepartment of Hepatology, Institute of Liver and Biliary Sciences, New Delhi 110070, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C Virus (HCV) genotype (GT) 6 demonstrates maximum genomic diversity out of all the known genotypes of HCV, attributable to its inherent intra-genotype and inter-genotype recombination property. This is the most common genotype seen in HCV/HIV co-infected cases. HIV/HCV co-infection is linked with increased genetic diversity in HCV structural genes. The detailed information on the distribution of HCV GT6, its subtypes, and resistance to currently available antiviral drugs is limited in the Indian subcontinent. Therefore, in this single-center retrospective cross-sectional study, we aimed to map the occurrence of HCV GT6, its subtypes and resistance-associated substitution (RAS), and its correlation with antiviral treatment response in HCV-infected patients. From a cohort of 2052 HCV-infected patients, the overall prevalence of GT6 was 2.5% (

Indexed as

CoinfectionHepatitis CHIV InfectionsCross-Sectional StudiesDrug ResistanceGenotypeHepacivirusHumansIndiaPhylogenyPilot ProjectsRetrospective Studieschronic hepatitis Cco-infectionHCV GT6HCV/HIVoccurrencephylogenetic analysisRASSVR

Identifiers

PMID35632686
PMCPMC9146731

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.