Evidence map›Paper›PMID 35633209›Full record

ArticleJNMA; journal of the Nepal Medical Association2022

Minimal Change Disease in an Adult: A Case Report.

Shashank Neupane, Prasamsa Pudasaini, Anupam Sharma, Shriya Sharma, Aakriti Adhikari, Kumar Roka

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JNMA; journal of the Nepal Medical Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shashank NeupaneNepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.
Prasamsa PudasainiNepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.
Anupam SharmaNepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.
Shriya SharmaNepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.
Aakriti AdhikariNepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.
Kumar RokaDepartment of Internal Medicine, Shree Birendra Hospital, Chhauni, Kathmandu, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Minimal change disease is an important cause of nephrotic syndrome in children, however, few cases are seen among adults. There is very little literature regarding the occurrence of minimal change disease in adults. We reported a case of a 63-year-old male who presented with the complaint of swelling around the eyes mostly during the morning for 18 days and frothing of urine for 7 days. On examination, the patient was ill-looking and had edema around the eyes and over the ankles. After preliminary investigations, renal biopsy was performed and electron microscopy revealed diffuse effacement of foot processes of visceral epithelial cells suggesting minimal change disease (podocytopathy). The patient has been treated with tablet prednisolone 60 mg per oral once daily, tablet ramipril 2.5 mg per oral once daily, and tablet torsemide 20 mg per oral twice daily. Hence, minimal change disease should also be considered as a differential diagnosis in adults presenting with the features of nephrotic syndrome. Keywords: electron microscopy; minimal change disease; nephrotic syndrome; prednisolone.

Indexed as

Nephrosis, LipoidNephrotic SyndromeAdultChildHumansMaleMiddle AgedPrednisolonePrednisolone

Identifiers

PMID35633209
PMCPMC9252239

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.