Evidence map›Paper›PMID 35633656›Full record

ArticleMediators of inflammation2022

Alterations of the Gut Microbiome in Chinese Zhuang Ethnic Patients with Sepsis.

Jieyang Yu, Hongping Li, Jingjie Zhao, Yanhua Huang, Chunlei Liu, Pengfei Yang, Dinggui Lu, Jian Song, Lingzhang Meng

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Higher abundance ofmSystems · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jieyang YuCenter for Systemic Inflammation Research (CSIR), School of Preclinical Medicine, Youjiang Medical University for Nationalities, Baise, Guangxi Province, China.ORCID https://orcid.org/0000-0001-9045-4898
Hongping LiNeonatal Intensive Care Unit, Shenzhen Children's Hospital, Shenzhen, Guangdong Province, China.ORCID https://orcid.org/0000-0002-3706-4791
Jingjie ZhaoLife Science and Clinical Research Center, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi Province, China.ORCID https://orcid.org/0000-0002-1582-2053
Yanhua HuangDepartment of Critical Care Medicine, People's Hospital of Baise, Baise, Guangxi Province, China.ORCID https://orcid.org/0000-0003-1672-5332
Chunlei LiuBaise Maternal and Child Hospital, Baise, Guangxi Province, China.ORCID https://orcid.org/0000-0002-7645-6501
Pengfei YangBaise Maternal and Child Hospital, Baise, Guangxi Province, China.ORCID https://orcid.org/0000-0003-0317-958X
Dinggui LuTrauma Center, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi Province, China.ORCID https://orcid.org/0000-0001-9077-5552
Jian SongCenter for Systemic Inflammation Research (CSIR), School of Preclinical Medicine, Youjiang Medical University for Nationalities, Baise, Guangxi Province, China.ORCID https://orcid.org/0000-0002-2459-7046
Lingzhang MengCenter for Systemic Inflammation Research (CSIR), School of Preclinical Medicine, Youjiang Medical University for Nationalities, Baise, Guangxi Province, China.ORCID https://orcid.org/0000-0003-4536-8709
Affiliated Hospital of Youjiang Medical University for Nationalities · CNBaise University · CNShenzhen Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Sepsis is characterized as a dysregulated host immune response to infection and has been known to be closely associated with the gut microbiome. This study was aimed at investigating the gut microbial profiles of Zhuang ethnic patients with sepsis. Method: Eleven Zhuang ethnic patients with sepsis and 20 healthy individuals (controls) were recruited at the Baise City People's Hospital, China. Their gut microbial community profiles were analyzed by 16S rRNA gene sequencing using the Illumina MiSeq system. Results: The gut microbial community of patients with sepsis was significantly altered compared to that of the healthy individuals based on the results of principal coordinate analysis and microbial ecological networks. Additionally, significantly lower microbial alpha diversity was observed in patients with sepsis than in healthy individuals. In particular, the enrichment of Conclusion: This study demonstrated significant differences in the gut microbiome between Zhuang ethnic patients with sepsis and healthy individuals. In the future, it is necessary to determine whether such alterations are the cause or consequence of sepsis.

Indexed as

Gastrointestinal MicrobiomeSepsisEthnicityEubacterialesFecesHumansRNA, Ribosomal, 16SRNA, Ribosomal, 16S

Identifiers

PMID35633656
PMCPMC9142305
OpenAlexW4285742832

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.