Evidence map›Paper›PMID 35634169›Full record

ArticleMaterials today. Bio2022

Smart implanted access port catheter for therapy intervention with pH and lactate biosensors.

Bruno Gil, Benny Lo, Guang-Zhong Yang, Salzitsa Anastasova

Open access · goldAbstract read
In one paragraph

Article in Materials today. Bio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Smart Catheters for Diagnosis, Monitoring, and Therapy.Advanced healthcare materials · 2026
    Review
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  3. Rise of implantable drugs: A chronicle of breakthroughs in drug delivery systems.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Bruno GilThe Hamlyn Centre, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.
Benny LoThe Hamlyn Centre, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.
Guang-Zhong YangInstitute of Medical Robotics, Shanghai Jiao Tong University, Shanghai, 200240, China.
Salzitsa AnastasovaThe Hamlyn Centre, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.
Imperial College London · GBShanghai Jiao Tong University · CN

Funding

Wellcome Trust 208857/Z/17/Z
6 · The paper itself

Abstract

Totally implanted access ports (TIAP) are widely used with oncology patients requiring long term central venous access for the delivery of chemotherapeutic agents, infusions, transfusions, blood sample collection and parenteral nutrition. Such devices offer a significant improvement to the quality of life for patients and reduced complication rates, particularly infection, in contrast to the classical central venous catheters. Nevertheless, infections do occur, with biofilm formation bringing difficulties to the treatment of infection-related complications that can ultimately lead to the explantation of the device. A smart TIAP device that is sensor-enabled to detect infection prior to extensive biofilm formation would reduce the cases for potential device explantation, whereas biomarkers detection within body fluids such as pH or lactate would provide vital information regarding metabolic processes occurring inside the body. In this paper, we propose a novel batteryless and wireless device suitable for the interrogation of such markers in an embodiment model of an TIAP, with miniature biochemical sensing needles. Device readings can be carried out by a smartphone equipped with Near Field Communication (NFC) interface at relative short distances off-body, while providing radiofrequency energy harvesting capability to the TIAP, useful for assessing patient's health and potential port infection on demand.

Indexed as

Batteryless deviceCentral venous catheterLactate sensorNear field communicationpH sensorTotally implanted access port

Identifiers

PMID35634169
PMCPMC9133618
OpenAlexW4280572590

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.