Evidence map›Paper›PMID 35634302›Full record

ArticleFrontiers in immunology2022

Distinct Injury Responsive Regulatory T Cells Identified by Multi-Dimensional Phenotyping.

Fei Guo, Brandon Hancock, Alec Griffith, Hui Lin, Kaitlyn Howard, Joshua Keegan, Fan Zhang, Adam Chicoine, Laura Cahill, Julie Ng and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Fei GuoDepartment of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Brandon HancockDepartment of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Alec GriffithDepartment of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Hui LinDepartment of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Kaitlyn HowardDepartment of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Joshua KeeganDepartment of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Fan ZhangDepartment of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Adam ChicoineHuman Immunology Center, Brigham and Women's Hospital, Boston, MA, United States.
Laura CahillDepartment of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Julie NgDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, United States.
James LedererDepartment of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Harvard University · USBrigham and Women's Hospital · USNingbo Medical Center Lihuili Hospital · CN

Funding

Therapy of acute radiation syndrome and its complications by mesenchymal stromal cells conditioned with Toll-like receptor 9 agonistsU01AI138318 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI LEDERER, JAMES A., PERRELLA, MARK A · 2018 to 2022
$3.1M
Restoring Immune Function Following Radiation Injuries by TLR9 Agonist TreatmentU01AI107360 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI LEDERER, JAMES A. · 2013 to 2017
$3.0M
Adaptive Immune Regulation of Traumatic InjuryR01AI148232 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI LEDERER, JAMES A. · 2020 to 2024
$2.1M
Injury-Specific Activation of the Immune SystemR01AI092905 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI LEDERER, JAMES A. · 2011 to 2015
$2.0M
NIAID NIH HHS R01 AI092905NIAID NIH HHS R01 AI148232NIAID NIH HHS U01 AI107360NIAID NIH HHS U01 AI138318
6 · The paper itself

Abstract

CD4

Indexed as

Receptors, Antigen, T-Cell, alpha-betaT-Lymphocytes, RegulatoryAnimalsCell ProliferationMiceReceptors, Antigen, T-Cell, alpha-betaCyTOFsingle-cell RNA sequencingT cell receptor diversitytrauma immunologyTregs

Identifiers

PMID35634302
PMCPMC9135044
OpenAlexW4283400069

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.