Evidence map›Paper›PMID 35643116›Full record

ArticleChest2022

Development and Internal Validation of a Prognostic Model of the Probability of Death or Lung Transplantation Within 2 Years for Patients With Cystic Fibrosis and FEV

Kathleen J Ramos, Travis Hee Wai, Anne L Stephenson, Jenna Sykes, Sanja Stanojevic, Patricia J Rodriguez, Aasthaa Bansal, Nicole Mayer-Hamblett, Christopher H Goss, Siddhartha G Kapnadak

Open access · greenAbstract read
In one paragraph

Article in Chest, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Linkage of the CF Foundation Patient Registry with the Scientific Registry of Transplant Recipients database.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Kathleen J RamosDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA. Electronic address: ramoskj@uw.edu.
Travis Hee WaiDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA.
Anne L StephensonDepartment of Respirology, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Jenna SykesDepartment of Respirology, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Sanja StanojevicTranslational Medicine, Hospital for Sick Children, Toronto, ON, Canada.
Patricia J RodriguezComparative Health Outcomes, Policy, and Economics (CHOICE) Institute, University of Washington, Seattle, WA.
Aasthaa BansalComparative Health Outcomes, Policy, and Economics (CHOICE) Institute, University of Washington, Seattle, WA.
Nicole Mayer-HamblettDivision of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA; Seattle Children's Research Institute, Seattle, WA.
Christopher H GossDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA; Division of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA; Seattle Children's Research Institute, Seattle, WA.
Siddhartha G KapnadakDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA.
University of Washington · USSt. Michael's Hospital · CAHospital for Sick Children · CASeattle Children's Hospital · US

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Institute of Translational Health SciencesUL1TR000423 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$49.4M
Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI PRADEEP k SINGH · 2010 to 2026
$21.4M
Proof of Principle Evaluation of IV Gallium Nitrate in Patients with CFUM1HL119073 · NHLBI · UNIVERSITY OF WASHINGTON · PI GOSS, CHRISTOPHER HOOPER, SINGH, PRADEEP K · 2013 to 2017
$4.8M
OPTIMIZE - DCCU01HL114589 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI HAMBLETT, NICOLE MAYER · 2013 to 2017
$3.3M
Personalized Risk-AdaptIve Surveillance strategies in cancEr -- PRAISER37CA218413 · NCI · UNIVERSITY OF WASHINGTON · PI BANSAL, AASTHAA · 2018 to 2024
$3.0M
Predicting survival and planning for lung transplantation in severe cystic fibrosisK23HL138154 · NHLBI · UNIVERSITY OF WASHINGTON · PI RAMOS, KATHLEEN JESSICA · 2017 to 2021
$947k
FDA HHS R01 FD003704FDA HHS R01 FD006848NCATS NIH HHS UL1 TR000423NCATS NIH HHS UL1 TR002319NCI NIH HHS R37 CA218413NHLBI NIH HHS K23 HL138154NHLBI NIH HHS U01 HL114589NHLBI NIH HHS UM1 HL119073NIDDK NIH HHS P30 DK089507
6 · The paper itself

Abstract

backgroundImproved methods are needed to risk-stratify patients with cystic fibrosis (CF) and reduced FEV RESEARCH QUESTIONS: What are the predictors of death or lung transplantation (LTx) within 2 years among patients with CF whose FEV STUDY DESIGN AND

methodsPatients with CF, age ≥ 6 years with FEV

resultsFEV

interpretationAmong individuals with CF and FEV

Indexed as

Cystic FibrosisLung TransplantationAminophenolsAnti-Bacterial AgentsChildHemoglobinsHumansOxygenProbabilityPrognosisQuinolonesAminophenolsAnti-Bacterial AgentsHemoglobinsivacaftorOxygenQuinolonesclassifier modelcystic fibrosisFEV(1)predictive model

Identifiers

PMID35643116
PMCPMC9633811
OpenAlexW4281552814

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.