Evidence map›Paper›PMID 35643587›Full record

ArticleJournal of substance abuse treatment2022

Multimorbidity classes indicate differential patterns of health care engagement among people who inject drugs.

Omeid Heidari, Becky L Genberg, Nancy Perrin, Derek T Dangerfield, Jason E Farley, Gregory Kirk, Shruti H Mehta

Abstract read
In one paragraph

Article in Journal of substance abuse treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Barriers and facilitators to primary care engagement for people who inject drugs: A systematic review.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Multimorbidity Patterns and Obesity Among Americans Turning Forty.American journal of health promotion : AJHP · 2026
    Article
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Omeid HeidariJohns Hopkins University, Bloomberg School of Public Health, Department of Mental Health, 615 N. Wolfe St, Baltimore, MD 21205, United States of America; Us Helping Us, People Into Living, Inc., 3636 Georgia Ave NW, Washington, D.C. 20010, United States of America. Electronic address: Oheidar1@jhu.edu.
Becky L GenbergJohns Hopkins University, Bloomberg School of Public Health, Department of Epidemiology, 615 N. Wolfe St, Baltimore, MD 21205, United States of America.
Nancy PerrinJohns Hopkins University, School of Nursing, 525 N. Wolfe St, Baltimore, MD, 21205, United States of America.
Derek T DangerfieldJohns Hopkins University, School of Nursing, 525 N. Wolfe St, Baltimore, MD, 21205, United States of America; Us Helping Us, People Into Living, Inc., 3636 Georgia Ave NW, Washington, D.C. 20010, United States of America.
Jason E FarleyThe Center for Infectious Disease and Nursing Innovation, Johns Hopkins University, School of Nursing, 525 N. Wolfe St, Baltimore, MD 21205, United States of America; Johns Hopkins University, School of Nursing, 525 N. Wolfe St, Baltimore, MD, 21205, United States of America.
Gregory KirkThe Center for Infectious Disease and Nursing Innovation, Johns Hopkins University, School of Nursing, 525 N. Wolfe St, Baltimore, MD 21205, United States of America.
Shruti H MehtaJohns Hopkins University, Bloomberg School of Public Health, Department of Epidemiology, 615 N. Wolfe St, Baltimore, MD 21205, United States of America.

Funding

The AIDS Linked to the Intravenous Experience (ALIVE) StudyU01DA036297 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Gregory D Kirk, Shruti H Mehta · 2014 to 2026
$28.9M
NIDA Epidemiology Training Program: Johns Hopkins UniversityT32DA007292 · NIDA · JOHNS HOPKINS UNIVERSITY · PI RENEE M. JOHNSON, Brion S Maher · 1993 to 2026
$17.7M
NIDA NIH HHS T32 DA007292NIDA NIH HHS U01 DA036297
6 · The paper itself

Abstract

backgroundAging people who inject drugs (PWID) have complex health needs. Health care management could be complicated by persistent substance use, multiple health challenges, and inconsistent access to care. However, we know little about the relationship between chronic multimorbidity and health care engagement in this population. The purpose of this study is to characterize patterns and correlates of chronic disease multimorbidity among PWID.

methodsWe conducted a latent class analysis (LCA) using data from the AIDS Linked to the IntraVenous Experience (ALIVE) Study, a community-based observational cohort, to determine classes of multimorbid chronic diseases. We then conducted regressions to determine factors associated with class membership and the impact of each multimorbid class on health events and utilization.

resultsOf 1387 individuals included, the majority were male (67%) and Black (81%), with a mean age of 53 years. We identified four classes of multimorbidity: Low Multimorbidity (54%), and Low Multimorbidity Including Psychiatric Comorbidity (26%), Multimorbidity (12%), and Multimorbidity Including Psychiatric Comorbidity (7%). Female sex, baseline age, and receipt of disability were factors significantly associated with membership in all three classes compared to the Low Multimorbidity class. Additionally, PWID in these three classes were significantly more likely to utilize emergency room and outpatient health care. Membership in both classes with psychiatric comorbidity was associated with significantly higher adjusted odds of receiving medication for opioid use disorder. DISCUSSION: Holistic health care systems can best address the needs of aging PWID with integrated care that provides harm reduction, substance use and mental health treatment together, and wrap around services.

Indexed as

Drug UsersOpioid-Related DisordersSubstance Abuse, IntravenousChronic DiseaseDelivery of Health CareFemaleHumansMaleMiddle AgedMultimorbidityChronic diseaseHealthcare utilizationLatent class analysisOpioid use

Identifiers

PMID35643587
PMCPMC10544774

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.