Evidence map›Paper›PMID 35646157›Full record

ArticleJournal of the renin-angiotensin-aldosterone system : JRAAS2022

The Association of Serum AIM2 Level with the Prediction and Short-Term Prognosis of Coronary Artery Disease.

Wenkang Zhang, Gaoliang Yan, Chunyang Xu, Chengchun Tang

Open access · hybridAbstract read
In one paragraph

Article in Journal of the renin-angiotensin-aldosterone system : JRAAS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. The role of absent in melanoma 2 (AIM2) in cardiovascular diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  4. Mechanisms underlying atrial fibrillation in chronic kidney disease.Journal of molecular and cellular cardiology · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Wenkang ZhangSchool of Medicine, Southeast University, Nanjing, Jiangsu 210009, China.ORCID https://orcid.org/0000-0001-8456-023X
Gaoliang YanDepartment of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, China.ORCID https://orcid.org/0000-0003-2563-167X
Chunyang XuSchool of Medicine, Southeast University, Nanjing, Jiangsu 210009, China.ORCID https://orcid.org/0000-0002-2015-7094
Chengchun TangDepartment of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, China.ORCID https://orcid.org/0000-0003-3767-3551
Southeast University · BDZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Coronary artery disease (CAD), one of the commonest cardiovascular diseases, has high morbidity and mortality. Absent in melanoma 2 (AIM2) is involved in atherosclerosis, and no clinical trials have explored the association between AIM2 and CAD. Therefore, this study was aimed at evaluating the predictive and short-term prognostic value of AIM2 for CAD. Methods: 279 patients who underwent coronary angiography were enrolled in this study. The AIM2 level was detected from the serum of collected artery blood samples. The association of serum AIM2 level with the prediction and short-term prognosis of CAD was further assessed. Results: The serum AIM2 level of the CAD group was significantly higher than the control group (5.5 ± 2.1 vs. 3.7 ± 1.7; Conclusions: The serum AIM2 level > 4.9 ng/mL can predict CAD to a certain extent. AIM2 might be an independent predictor of its short-term poor prognosis.

Indexed as

Coronary Artery DiseaseDNA-Binding ProteinsCoronary AngiographyHumansPrognosisROC CurveAIM2 protein, humanDNA-Binding Proteins

Identifiers

PMID35646157
PMCPMC9124122
OpenAlexW4280525717

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.