Evidence map›Paper›PMID 35646663›Full record

ArticleFrontiers in oncology2022

Characterization of Anti-Cancer Activities of Violacein: Actions on Tumor Cells and the Tumor Microenvironment.

Charlotte Dahlem, Shilpee Chanda, Jan Hemmer, Hanna S Schymik, Michael Kohlstedt, Christoph Wittmann, Alexandra K Kiemer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Violacein-Loaded Outer Membrane Vesicles fromACS biomaterials science & engineering · 2025
    Article
  5. Pigments from pathogenic bacteria: a comprehensive update on recent advances.World journal of microbiology & biotechnology · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Charlotte DahlemPharmaceutical Biology, Department of Pharmacy, Saarland University, Saarbruecken, Germany.
Shilpee ChandaPharmaceutical Biology, Department of Pharmacy, Saarland University, Saarbruecken, Germany.
Jan HemmerPharmaceutical Biology, Department of Pharmacy, Saarland University, Saarbruecken, Germany.
Hanna S SchymikPharmaceutical Biology, Department of Pharmacy, Saarland University, Saarbruecken, Germany.
Michael KohlstedtInstitute of Systems Biotechnology, Saarland University, Saarbruecken, Germany.
Christoph WittmannInstitute of Systems Biotechnology, Saarland University, Saarbruecken, Germany.
Alexandra K KiemerPharmaceutical Biology, Department of Pharmacy, Saarland University, Saarbruecken, Germany.
Saarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural products have been shown to serve as promising starting points for novel anti-cancer drugs. In this study, the anti-cancer activities of the purple compound violacein, initially isolated from

Indexed as

chemoresistanceIL1βIL6immunogenicityiNOSnatural compoundsreactive oxygen speciesTNF

Identifiers

PMID35646663
PMCPMC9130777
OpenAlexW4280606247

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.