Evidence map›Paper›PMID 35648225›Full record

ReviewCellular and molecular life sciences : CMLS2022

Oxidative stress response pathways in fungi.

Hajar Yaakoub, Sara Mina, Alphonse Calenda, Jean-Philippe Bouchara, Nicolas Papon

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 151 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. HOG Signaling: A Multifunctional Regulator of Stress Homeostasis inJournal of fungi (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Mitochondrial localization of key NADApplied and environmental microbiology · 2026
    Article
  8. Review
  9. Early Cellular Responses ofAntibiotics (Basel, Switzerland) · 2026
    Article
  10. Review
  11. Article
  12. Opportunistic pathogenicity in fungi can transcend species boundaries.bioRxiv : the preprint server for biology · 2026
    Article
  13. Journal of fungi (Basel, Switzerland) · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Oxidative pre-stress ofFood chemistry: X · 2026
    Article
  18. Article
  19. Article
  20. Article

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Hajar Yaakoub *Univ Angers, Univ Brest, IRF, SFR ICAT, 49000, Angers, France.
Sara Mina *Department of Medical Laboratory Sciences, Faculty of Health Sciences, Beirut Arab University, Beirut, Lebanon.
Alphonse CalendaUniv Angers, Univ Brest, IRF, SFR ICAT, 49000, Angers, France.
Jean-Philippe BoucharaUniv Angers, Univ Brest, IRF, SFR ICAT, 49000, Angers, France. jean-philippe.bouchara@univ-angers.fr.
Nicolas PaponUniv Angers, Univ Brest, IRF, SFR ICAT, 49000, Angers, France. nicolas.papon@univ-angers.fr.ORCID http://orcid.org/0000-0001-6265-7321
Université de Bretagne Occidentale · FRBeirut Arab University · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal response to any stress is intricate, specific, and multilayered, though it employs only a few evolutionarily conserved regulators. This comes with the assumption that one regulator operates more than one stress-specific response. Although the assumption holds true, the current understanding of molecular mechanisms that drive response specificity and adequacy remains rudimentary. Deciphering the response of fungi to oxidative stress may help fill those knowledge gaps since it is one of the most encountered stress types in any kind of fungal niche. Data have been accumulating on the roles of the HOG pathway and Yap1- and Skn7-related pathways in mounting distinct and robust responses in fungi upon exposure to oxidative stress. Herein, we review recent and most relevant studies reporting the contribution of each of these pathways in response to oxidative stress in pathogenic and opportunistic fungi after giving a paralleled overview in two divergent models, the budding and fission yeasts. With the concept of stress-specific response and the importance of reactive oxygen species in fungal development, we first present a preface on the expanding domain of redox biology and oxidative stress.

Indexed as

Oxidative StressSchizosaccharomycesReactive Oxygen SpeciesReactive Oxygen SpeciesFungal adaptationFungal pathogensHog1Oxidative stressSkn7Yap1

Identifiers

PMID35648225
PMCPMC11071803
OpenAlexW4281991377

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.