Evidence map›Paper›PMID 35649693›Full record

ArticleLife science alliance2022

VDAC1 negatively regulates melanogenesis through the Ca

Jianli Wang, Juanjuan Gong, Qiaochu Wang, Tieshan Tang, Wei Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life science alliance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jianli WangBeijing Key Laboratory for Genetics of Birth Defects, Beijing Pediatric Research Institute; MOE Key Laboratory of Major Diseases in Children; Rare Disease Center, National Center for Children's Health; Beijing Children's Hospital, Capital Medical University, Beijing, China.
Juanjuan GongBeijing Key Laboratory for Genetics of Birth Defects, Beijing Pediatric Research Institute; MOE Key Laboratory of Major Diseases in Children; Rare Disease Center, National Center for Children's Health; Beijing Children's Hospital, Capital Medical University, Beijing, China.
Qiaochu WangBeijing Key Laboratory for Genetics of Birth Defects, Beijing Pediatric Research Institute; MOE Key Laboratory of Major Diseases in Children; Rare Disease Center, National Center for Children's Health; Beijing Children's Hospital, Capital Medical University, Beijing, China.
Tieshan TangState Key Laboratory of Membrane Biology, Institute of Zoology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, China.
Wei LiBeijing Key Laboratory for Genetics of Birth Defects, Beijing Pediatric Research Institute; MOE Key Laboratory of Major Diseases in Children; Rare Disease Center, National Center for Children's Health; Beijing Children's Hospital, Capital Medical University, Beijing, China liwei@bch.com.cn.ORCID https://orcid.org/0000-0002-0248-5510
Capital Medical University · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanocytes produce melanin for protecting DNA from ultraviolet exposure to maintain genomic stability. However, the precise regulation of melanogenesis is not fully understood. VDAC1, which is mainly localized in the outer mitochondrial membrane, functions as a gatekeeper for the entry or exit of Ca

Indexed as

CalcineurinMelanomaVoltage-Dependent Anion Channel 1AnimalsMelaninsMelanocytesMiceMicrophthalmia-Associated Transcription FactorTranscription FactorsCalcineurinCrtc1 protein, mouseMelaninsMicrophthalmia-Associated Transcription FactorMitf protein, mouseTranscription FactorsVdac1 protein, mouseVoltage-Dependent Anion Channel 1

Identifiers

PMID35649693
PMCPMC9160443
OpenAlexW4281700691

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.