Evidence map›Paper›PMID 35651616›Full record

ArticleFrontiers in immunology2022

Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of

Ann E Sluder, Susan Raju Paul, Leonard Moise, Christina Dold, Guilhem Richard, Laura Silva-Reyes, Laurie A Baeten, Anja Scholzen, Patrick M Reeves, Andrew J Pollard and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  10. Cytometry profiling ofFrontiers in immunology · 2023
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  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Ann E SluderVaccine and Immunotherapy Center, Massachusetts General Hospital, Boston, MA, United States.
Susan Raju PaulVaccine and Immunotherapy Center, Massachusetts General Hospital, Boston, MA, United States.
Leonard MoiseEpiVax, Inc., Providence, RI, United States.
Christina DoldOxford Vaccine Group, Department of Paediatrics, The National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.
Guilhem RichardEpiVax, Inc., Providence, RI, United States.
Laura Silva-ReyesOxford Vaccine Group, Department of Paediatrics, The National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.
Laurie A BaetenDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO, United States.
Anja ScholzenInnatoss Laboratories B.V., Oss, Netherlands.
Patrick M ReevesVaccine and Immunotherapy Center, Massachusetts General Hospital, Boston, MA, United States.
Andrew J PollardOxford Vaccine Group, Department of Paediatrics, The National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.
Anja GarritsenInnatoss Laboratories B.V., Oss, Netherlands.
Richard A BowenDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO, United States.
Anne S De GrootEpiVax, Inc., Providence, RI, United States.
Christine RollierOxford Vaccine Group, Department of Paediatrics, The National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.
Mark C PoznanskyVaccine and Immunotherapy Center, Massachusetts General Hospital, Boston, MA, United States.
Massachusetts General Hospital · USNational Institute for Health Research · GBColorado State University · USEpiVax (United States) · USProvidence College · USUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T cell-mediated immunity plays a central role in the control and clearance of intracellular

Indexed as

Coxiella burnetiiQ FeverAnimalsAntibodies, BacterialBacterial VaccinesDisease Models, AnimalEpitopes, T-LymphocyteGuinea PigsHumansMiceMice, Inbred C57BLPeptidesT-LymphocytesAntibodies, BacterialBacterial VaccinesEpitopes, T-LymphocytePeptidesChAdOx2Coxiella burnetiiinterferon gamma (IFNγ)modified vaccinia Ankara (MVA)multi-epitope vaccinenon-human primate (NHP)Q feverT cell vaccine

Identifiers

PMID35651616
PMCPMC9149306
OpenAlexW4280653793

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.