Evidence map›Paper›PMID 35653735›Full record

ArticleHigh altitude medicine & biology2022

Exposure to High Altitude Promotes Loss of Muscle Mass That Is Not Rescued by Metformin.

Zackery S Fullerton, Benjamin D McNair, Nicholas A Marcello, Emily E Schmitt, Danielle R Bruns

Open access · greenAbstract read
In one paragraph

Article in High altitude medicine & biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Advancing high-altitude medicine: a model for the future.Signal transduction and targeted therapy · 2026
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zackery S FullertonDivision of Kinesiology and Health, University of Wyoming, Laramie, Wyoming, USA.
Benjamin D McNairDivision of Kinesiology and Health, University of Wyoming, Laramie, Wyoming, USA.
Nicholas A MarcelloDivision of Kinesiology and Health, University of Wyoming, Laramie, Wyoming, USA.
Emily E SchmittDivision of Kinesiology and Health, University of Wyoming, Laramie, Wyoming, USA.ORCID 0000-0001-6965-9768
Danielle R BrunsDivision of Kinesiology and Health, University of Wyoming, Laramie, Wyoming, USA.
University of Wyoming · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fullerton, Zackery S., Benjamin D. McNair, Nicholas A. Marcello, Emily E. Schmitt, and Danielle R. Bruns. Exposure to high altitude promotes loss of muscle mass that is not rescued by metformin.

Indexed as

MetforminMyostatinAltitudeAnimalsFemaleMaleMiceMice, Inbred C57BLMusclesMuscle, SkeletalMuscular AtrophyMetforminMyostatinhigh altitudehypoxiametforminmuscle atrophy

Identifiers

PMID35653735
PMCPMC9526469
OpenAlexW4281740660

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.