Evidence map›Paper›PMID 35654349›Full record

ReviewJournal of ethnopharmacology2022

An exhaustive comprehension of the role of herbal medicines in Pre- and Post-COVID manifestations.

Shiv Kumar Prajapati, Akanksha Malaiya, Gaurav Mishra, Dolly Jain, Payal Kesharwani, Nishi Mody, Amirhossein Ahmadi, Rishi Paliwal, Ankit Jain

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of ethnopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Natural Ingredients to Improve Immunity.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  5. Article
  6. The Cultural and Commercial Value of Tulsi (Plants (Basel, Switzerland) · 2022
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Shiv Kumar PrajapatiInstitute of Pharmacy, Ram-Eesh Institute of Vocational and Technical Education, Greater Noida, 201310, UP, India.
Akanksha MalaiyaNanomedicine and Bioengineering Research Laboratory, Department of Pharmacy, Indira Gandhi National Tribal University, Amarkantak, 484886, MP, India.
Gaurav MishraInstitute of Medical Sciences, Faculty of Ayurveda, Department of Medicinal Chemistry, Banaras Hindu University, Varanasi, 221005, UP, India.
Dolly JainDepartment of Pharmacy, Oriental University, Indore, 453555, Madhya Pradesh, India; Adina College of Pharmacy, Sagar, 470002, MP, India.
Payal KesharwaniInstitute of Pharmacy, Ram-Eesh Institute of Vocational and Technical Education, Greater Noida, 201310, UP, India.
Nishi ModyDepartment of Pharmaceutical Sciences, Dr. Harisingh Gour University, Sagar, 470003, MP, India.
Amirhossein AhmadiPharmaceutical Sciences Research Centre, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, 48175866, Iran.
Rishi PaliwalNanomedicine and Bioengineering Research Laboratory, Department of Pharmacy, Indira Gandhi National Tribal University, Amarkantak, 484886, MP, India.
Ankit JainDepartment of Materials Engineering, Indian Institute of Science, Bangalore, 560012, Karnataka, India. Electronic address: ankitjainsagar@gmail.com.
Indira Gandhi National Tribal University · INDevi Ahilya Vishwavidyalaya · INDr. Hari Singh Gour University · INIndian Institute of Science Bangalore · INInstitute of Medical Sciences · INMazandaran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ethnopharmacological relevanceThe coronavirus disease (COVID-19) has relentlessly spread all over the world even after the advent of vaccines. It demands management, treatment, and prevention as well with utmost safety and effectiveness. It is well researched that herbal medicines or natural products have shown promising outcomes to strengthen immunity with antiviral potential against SARS-COV-2. AIM OF THE REVIEW: Our objective is to provide a comprehensive insight into the preventive and therapeutic effects of herbal medicines and products (Ayurvedic) for pre-and post-COVID manifestations. MATERIAL AND

methodThe database used in the text is collected and compiled from Scopus, PubMed, Nature, Elsevier, Web of Science, bioRxiv, medRxiv, American Chemical Society, and clinicaltrials.gov up to January 2022. Articles from non-academic sources such as websites and news were also retrieved. Exploration of the studies was executed to recognize supplementary publications of research studies and systematic reviews. The keywords, such as "SARS-COV-2, coronavirus, COVID-19, herbal drugs, immunity, herbal immunomodulators, infection, herbal antiviral drugs, and WHO recommendation" were thoroughly searched. Chemical structures were drawn using the software Chemdraw Professional 15.0.0.160 (PerkinElmer Informatics, Inc.).

resultA plethora of literature supports that the use of herbal regimens not only strengthen immunity but can also treat SARS-COV-2 infection with minimal side effects. This review summarizes the mechanistic insights into herbal therapy engaging interferons and antibodies to boost the response against SARS-COV-2 infection, several clinical trials, and in silico studies (computational approaches) on selected natural products including, Ashwagandha, Guduchi, Yashtimadhu, Tulsi, etc. as preventive and therapeutic measures against COVID. We have also emphasized the exploitation of herbal medicine-based pharmaceutical products along with perspectives for unseen upcoming alike diseases.

conclusionAccording to the current state of art and cutting-edge research on herbal medicines have showed a significant promise as modern COVID tools. Since vaccination cannot be purported as a long-term cure for viral infections, herbal/natural medicines can only be considered a viable alternative to current remedies, as conceived from our collected data to unroot recurring viral infections.

Indexed as

COVID-19 Drug TreatmentDrugs, Chinese HerbalPlants, MedicinalAntiviral AgentsComprehensionHumansSARS-CoV-2Antiviral AgentsDrugs, Chinese HerbalCoronavirusHerbal medicineImmunomodulationPharmaceutical productSARS-COV-2

Identifiers

PMID35654349
PMCPMC9150915
OpenAlexW4281641466

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.