Evidence map›Paper›PMID 35656114›Full record

ReviewAging and disease2022

Stem Cell-derived Exosomal MicroRNA as Therapy for Vascular Age-related Diseases.

Hang Ren, Ziyuan Guo, Yang Liu, Chunli Song

Open access · goldAbstract readReview
In one paragraph

Review in Aging and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Microvascular Health as a Key Determinant of Organismal Aging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Review
  3. Review
  4. The interplay of exosomal miRNAs in hypertension and aging.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hang RenDepartment of Cardiovascular Internal Medicine, the Second Hospital of Jilin University, Changchun, China.
Ziyuan GuoDepartment of Cardiovascular Internal Medicine, the Second Hospital of Jilin University, Changchun, China.
Yang LiuDepartment of Cardiovascular Internal Medicine, the Second Hospital of Jilin University, Changchun, China.
Chunli SongDepartment of Cardiovascular Internal Medicine, the Second Hospital of Jilin University, Changchun, China.
Second Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular age-related diseases describe a group of age-related chronic diseases that result in a considerable healthcare burden to society. Vascular aging includes structural changes and dysfunctions of endothelial cells (ECs) and smooth muscle cells (SMCs) in blood vessels. Compared with conventional treatment for vascular age-related diseases, stem cell (SC) therapy elicits better anti-aging effects

Indexed as

MicroRNAssenescencestem cell-derived exosomal microRNAvascular age-related diseases

Identifiers

PMID35656114
PMCPMC9116915
OpenAlexW4282933973

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.