Evidence map›Paper›PMID 35659577›Full record

ReviewAlcohol (Fayetteville, N.Y.)2022

New insights into the mechanism of alcohol-mediated organ damage via its impact on immunity, metabolism, and repair pathways: A summary of the 2021 Alcohol and Immunology Research Interest Group (AIRIG) meeting.

Shanawaj Khair, Lisa A Brenner, Michael Koval, Derrick Samuelson, Jessica A Cucinello-Regland, Paige Anton, Mariann R Piano, Liz Simon, Kathryn Crotty, Farah Sharieh and 10 more

Open access · greenAbstract readReview
In one paragraph

Review in Alcohol (Fayetteville, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 12 institutions in 1 country.

Shanawaj KhairDepartment of Surgery, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States; Alcohol Research Program, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States; Molecular Biology Graduate Program, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States; Medical Scientist Training Program, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States.
Lisa A BrennerVA Rocky Mountain Mental Illness Research Education and Clinical Center, Rocky Mountain Regional Veterans Affairs (VA) Medical Center, Aurora, CO, United States; Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Department of Psychiatry and Neurology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Military and Veteran Microbiome: Consortium for Research and Education, Aurora, CO, United States.
Michael KovalDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA, United States; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, United States.
Derrick SamuelsonDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, United States.
Jessica A Cucinello-ReglandDepartment of Physiology, Alcohol and Drug Abuse Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Paige AntonDepartment of Pharmaceutical Sciences, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States.
Mariann R PianoCenter for Research Development and Scholarship, Vanderbilt University School of Nursing, Nashville, TN, United States.
Liz SimonDepartment of Physiology, Comprehensive Alcohol HIV/AIDs Research Center, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Kathryn CrottyDivision of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Atlanta Veterans Affairs Health Care System, Decatur, GA, United States.
Farah ShariehDepartment of Orthopedic Surgery and Rehabilitation, Loyola University Medical Center, Maywood, IL, United States; Alcohol Research Program, Loyola University Chicago Stritch School of Medicine, Maywood, IL, United States.
Jeffrey B TraversWright State University, Dayton VAMC, Dayton, OH, United States.
Vaibhav SinghDepartment of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH, United States.
Abigail CannonAlcohol Research Program, Burn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States.
Adam KimDepartment of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH, United States.
Rebecca L McCulloughDepartment of Pharmaceutical Sciences, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States.
Samantha M YeligarDivision of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, Atlanta Veterans Affairs Health Care System, Decatur, GA, United States.
Todd A WyattDepartment of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, United States; Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, NE, United States.
Rachel H McMahanDepartment of Surgery, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States; Alcohol Research Program, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States.
Mashkoor A ChoudhryAlcohol Research Program, Burn and Shock Trauma Research Institute, Department of Surgery, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States; Integrative Cell Biology Program, Loyola University Chicago Health Sciences Campus, Maywood, IL, United States.
Elizabeth J KovacsDepartment of Surgery, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States; Alcohol Research Program, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States; Molecular Biology Graduate Program, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States; Medical Scientist Training Program, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, United States; VA Rocky Mountain Mental Illness Research Education and Clinical Center, Rocky Mountain Regional Veterans Affairs (VA) Medical Center, Aurora, CO, United States. Electronic address: Elizabeth.Kovacs@CUAnschutz.edu.
University of Colorado Anschutz Medical Campus · USAtlanta VA Health Care System · USCleveland Clinic · USLouisiana State University Health Sciences Center New Orleans · USLoyola University Chicago · USUniversity of Colorado Denver · USEmory University · USLoyola University Medical Center · USUniversity of Nebraska Medical Center · USVanderbilt University · USVA Nebraska Western Iowa Health Care System · USWright State University · US

Funding

Project Two - Exercise Training Decreases Alcohol Drinking by an FGF21-Dependent MechanismP50AA024333 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI Srinivasan Dasarathy · 2016 to 2026
$19.6M
Electrophysiology of alcohol in extended amygdelaU01AA013498 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI MARISA ROBERTO · 2001 to 2026
$12.6M
Platelet Activating Factor and Epidermic CytotoxicityR01HL062996 · NHLBI · WRIGHT STATE UNIVERSITY · PI TRAVERS, JEFFREY B. · 1999 to 2023
$7.2M
Regulation of Ethanol Effects on Synaptic TransmissionR01AA015566 · NIAAA · SCRIPPS RESEARCH INSTITUTE, THE · PI ROBERTO, MARISA · 2006 to 2019
$4.6M
Training in Neuroimmunoendocrine Effects of AlcoholT32AA013527 · NIAAA · LOYOLA UNIVERSITY CHICAGO · PI CHOUDHRY, MASHKOOR A · 2002 to 2021
$4.4M
Alcohol and Burn Trauma: Multi-organ Inflammatory ResponsesR35GM131831 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI ELIZABETH J. KOVACS · 2019 to 2026
$3.5M
Transcriptional and non-transcriptional functions of IRF3 in ALDR01AA027456 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI LAURA E. NAGY · 2019 to 2026
$3.5M
TRAINING IN TRAUMA AND BURN RESEARCHT32GM008750 · NIGMS · LOYOLA UNIVERSITY CHICAGO · PI CHOUDHRY, MASHKOOR A, GONZALEZ, RICHARD PAUL · 2000 to 2023
$2.9M
Alcohol and the alveolar epithelial barrierR01AA025854 · NIAAA · EMORY UNIVERSITY · PI KOVAL, MICHAEL H. · 2017 to 2021
$1.9M
Biological Signature and Safety of an Immunomodulatory Probiotic Intervention of Veterans with PTSDR01AT010005 · NCCIH · UNIVERSITY OF COLORADO DENVER · PI BRENNER, LISA A, LOWRY, CHRISTOPHER A · 2020 to 2025
$1.8M
Alcohol-Induced Mitochondrial Derangements Cause Alveolar Macrophage DysfunctionR01AA026086 · NIAAA · EMORY UNIVERSITY · PI YELIGAR, SAMANTHA M. · 2018 to 2022
$1.8M
UVB radiation-generated microvesicle particles as effectors for photosensitivityR01ES031087 · NIEHS · WRIGHT STATE UNIVERSITY · PI KEMP, MICHAEL GEORGE, TRAVERS, JEFFREY B. · 2021 to 2025
$1.7M
BLRD VA I01 BX000853BLRD VA I01 BX004335BLRD VA I01 BX005413BLRD VA IK6 BX003781BLRD VA IK6 BX005962BLRD VA IS1 BX004790NCCIH NIH HHS R01 AT010005NHLBI NIH HHS R01 HL062996NIAAA NIH HHS F31 AA028147NIAAA NIH HHS F31 AA029938NIAAA NIH HHS L40 AA021555NIAAA NIH HHS P50 AA024333NIAAA NIH HHS R00 AA025386NIAAA NIH HHS R00 AA026336NIAAA NIH HHS R01 AA015566NIAAA NIH HHS R01 AA025854NIAAA NIH HHS R01 AA025996NIAAA NIH HHS R01 AA026086NIAAA NIH HHS R01 AA027456NIAAA NIH HHS R13 AA020768NIAAA NIH HHS R21 AA021225NIAAA NIH HHS R21 AA026295NIAAA NIH HHS T32 AA013527NIAAA NIH HHS U01 AA013498NIAAA NIH HHS U01 AA026938NIEHS NIH HHS R01 ES031087NIGMS NIH HHS R35 GM131831NIGMS NIH HHS T32 GM008750RRD VA I21 RX002232
6 · The paper itself

Abstract

On November 19th, 2021, the annual Alcohol and Immunology Research Interest Group (AIRIG) meeting was held at Loyola University Chicago Health Sciences Campus in Maywood, Illinois. The 2021 meeting focused on how alcohol misuse is linked to immune system derangements, leading to tissue and organ damage, and how this research can be translated into improving treatment of alcohol-related disease. This meeting was divided into three plenary sessions: the first session focused on how alcohol misuse affects different parts of the immune system, the second session presented research on mechanisms of organ damage from alcohol misuse, and the final session highlighted research on potential therapeutic targets for treating alcohol-mediated tissue damage. Diverse areas of alcohol research were covered during the meeting, from alcohol's effect on pulmonary systems and neuroinflammation to epigenetic changes, senescence markers, and microvesicle particles. These presentations yielded a thoughtful discussion on how the findings can lead to therapeutic treatments for people suffering from alcohol-related diseases.

Indexed as

AlcoholismEpigenesis, GeneticEthanolHumansInflammationPublic OpinionEthanolbraincardiovascular diseaseethanolinflammationliverlungmyopathypneumoniaskinstem cell

Identifiers

PMID35659577
PMCPMC9994264
OpenAlexW4281915817

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.