ArticleFrontiers in public health2022
Relationship Between Lipid Profiles and Hypertension: A Cross-Sectional Study of 62,957 Chinese Adult Males.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 67 citations in OpenAlex.
- Effect and mechanism of HMG-CoA reductase inhibitor on the improvement of elderly essential hypertension-induced vascular endothelial function impairment based on the JAK/STAT pathway.Diagnostic pathology · 2023Trial
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- Global DNA methylation and hypertension control Vis-À-Vis lipids: an exploratory population based study from rural Punjab, India.Journal of human hypertension · 2026Article
- Association of non-conventional lipid-inflammatory parameters with incident hypertension risk: a prospective cohort study.Journal of global health · 2026Article
- A clinically practical aging clock (physical clock) for healthy aging: development, validation, and application for health assessment and intervention.Science China. Life sciences · 2026Article
- Development of a Sex-Specific Prevalent Hypertension Discrimination Model in Korean Adults Using Genetic Risk Scores and Clinical Biomarkers: A Cross-Sectional Study.Current issues in molecular biology · 2026Article
- Molecular Interplay between hypertension and dyslipidemia in cardiovascular pathogenesis: toward precision-based therapeutic strategies.Frontiers in cardiovascular medicine · 2026Review
- Prevalence and Associated Factors of Hypertension Among Diabetic Individuals in the Sylhet Region of Bangladesh.International journal of hypertension · 2026Article
- Aerobic fitness, lipid ratio, visceral adiposity index and risk of hypertension in adolescents: An observational study.World journal of clinical pediatrics · 2025Article
- Development and Validation of an Explainable Prediction Model to Assess the Risk of Coronary Artery Disease in Young and Middle-Aged Individuals.Reviews in cardiovascular medicine · 2025Article
- Stress hyperglycemia ratio and incident hypertension in chinese middle-aged and older adults: mediating roles of lipids in a prospective cohort.Lipids in health and disease · 2025Article
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- U-shaped relationship between the non-HDL to HDL cholesterol ratio and mortality in hypertensive individuals in the study from NHANES database.Scientific reports · 2025Article
- Pro-Inflammatory Markers in Serum and Saliva in Periodontitis and Hypertension.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- Cross-validation of prediction equations for estimating the body mass index in adults without the use of body weight.PloS one · 2025Article
- Association between triglyceride-glucose index multiplied by waist circumference and H-type hypertension among Chinese adults.Frontiers in cardiovascular medicine · 2025Article
- The Association between Serum Lipid Profile Levels and Hypertension Grades: A Cross-Sectional Study at a Health Examination Center.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Article
- Remnant cholesterol, not LDL cholesterol, is associated with the risk of hypertension in the middle-aged and elderly population: Bushehr Elderly Health cohort.Frontiers in cardiovascular medicine · 2025Article
- Correlation between cholesterol and ambulatory blood pressure in postmenopausal osteoporotic patients: aFrontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Patterns of dyslipidemia and incidence of hypertension have been rarely reported in Asian populations with inconsistent findings. To accumulate further evidence in Asian populations, the study aimed to investigate the relationship between lipid profiles and hypertension in Chinese adult males. Methods: We conducted a cross-sectional study based on the data from the DATADRYAD database. The overall population was divided into hypertensive and non-hypertensive groups based on baseline blood pressure levels. For continuous variables, Mann-Whitney test was performed between two groups, while Kruskal-Wallis and Dunn tests were used among multiple groups. The chi-square test was carried out for dichotomous variables. Spearman's correlation coefficient was employed to assess the association between systolic blood pressure (SBP), diastolic blood pressure (DBP) and lipid profiles, whereas the relationship between lipid profiles and the incidence of hypertension was evaluated using multivariate logistic regression. The Bayesian network (BN) model was adopted to investigate the relationship between clinical characteristics and hypertension, and the importance of related predictor to the incidence of hypertension was obtained to make conditional probability analysis. Results: Finally, totally 62,957 participants were included in this study. In the lipid profiles, total cholesterol (TC), low-density cholesterol (LDL-c), and non- high-density lipoprotein cholesterol (non-HDL-c) were higher in the hypertensive population ( Conclusion: Elevated TC, LDL-c, and non-HDL-c were related to incidence of hypertension in Chinese adult males, whereas triglycerides (TG) was not significantly associated. The relationship between HDL-c and hypertension incidence shifted from no association to a positive correlation after adjusting for the BMI. Moreover, the BN model displayed that age, the BMI, FPG, and TC were strongly associated with hypertension incidence.
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