ArticleEvidence-based complementary and alternative medicine : eCAM2022
Traditional Chinese Medicine Constitution Is Associated with the Frailty Status of Older Adults: A Cross-Sectional Study in the Community.
Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Association between Traditional Chinese Medicine constitution and geriatric functional impairment evaluated by the integrated care for older people approach in the elderly.Journal of traditional and complementary medicine · 2026Article
- Article
- Defining Frailty in Chinese-Language Biomedical Literature (2014-2024): A Decade of Conceptual Evolution.Aging medicine (Milton (N.S.W)) · 2026Review
- TCM Constitution and the Risk of Hyperglycemia in Young and Middle-Aged Adults: A Retrospective Cohort Study.Journal of diabetes research · 2026Article
- Clinical validation of the Integrative Vitality Scale: a screening and patient-centered assessment tool for frailty and depressive disorders.Frontiers in public health · 2026Observational
- Traditional Chinese Medicine Constitution and Cognitive Frailty in Older Adults: Prediction Models and Sleep-Quality Mediation Pathway from a Multicenter Study in China.Clinical interventions in aging · 2025Article
- Article
- Development and Validation of the Chinese Frailty Screening Scale: A Study among Community-Dwelling Older Adults in Shanghai.International journal of environmental research and public health · 2022Article
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Authors and funding
11 authors.
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Abstract
Objective: This study explored the relationship between traditional Chinese medicine (TCM) constitution and frailty status in older adults. Methods: A total of 3,586 participants, 65 years of age and older, with complete data were evaluated. All received a complete frailty assessment and completed a TCM geriatric constitution questionnaire. Baseline characteristics and demographic information were collected. The relationship between the TCM constitution and frailty was evaluated by binary regression analysis. The consistency of the result was tested by multivariate linear regression. Results: The average prevalence of frailty among older adult participants was 12.5%. The three most prevalent biased constitutions in the frail older adult participants were phlegm dampness 140 (31.3%), Yin deficiency 77 (17.2%), and Yang deficiency 47 (10.5%). Univariate analysis showed that TCM constitution significantly correlated with frailty. After adjusting for potential confounders, binary logistic regression found a significant correlation between biased constitutions and frailty, including Qi stagnation (odds ratio (OR) = 3.51, 95% confidence interval (CI): 1.94-6.36)), Qi deficiency ((OR = 3.23, (95% CI: 1.76-5.94)), Yang deficiency ((OR = 2.37, (95% CI: 1.50-3.74)), phlegm dampness ((OR = 1.75, (95% CI: 1.24-2.48)), and Yin deficiency ((OR = 1.70, (95% CI: 1.15-2.50)). Results of multiple linear regression were consistent. Conclusions: TCM constitution was significantly associated with frailty status in older adults, and the distribution was different. Compared with a neutral constitution, older adults with Qi stagnation, Qi deficiency, Yang deficiency, phlegm dampness, and Yin deficiency were more likely to experience frailty.
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Registered trials
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