Evidence map›Paper›PMID 35666127›Full record

ArticleeLife2022

Cross-modality synthesis of EM time series and live fluorescence imaging.

Anthony Santella, Irina Kolotuev, Caroline Kizilyaprak, Zhirong Bao

Abstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. A pilot study for whole proteome tagging inbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. The 3D Ultrastructure ofmicroPublication biology · 2026
    Article
  6. Embryonic Development of Caenorhabditis elegans Sense Organs.The Journal of comparative neurology · 2025
    Article
  7. Analysis of developmental gene expression using smFISH andbioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anthony Santella *Molecular Cytology Core, Memorial Sloan Kettering Cancer Center, New York, United States.
Irina Kolotuev *Electron Microscopy Facility, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-1433-8048
Caroline KizilyaprakElectron Microscopy Facility, University of Lausanne, Lausanne, Switzerland.
Zhirong BaoDevelopmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, United States.ORCID 0000-0002-2201-2745

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
WormGUIDES: A Resource for Global Understanding in Dynamic Embryonic SystemsR24OD016474 · OD · YALE UNIVERSITY · PI BAO, ZHIRONG, COLON-RAMOS, DANIEL A · 2013 to 2020
$6.5M
The Ubiquitin-Proteasome System in Metazoan EmbryogenesisR01GM097576 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI BAO, ZHIRONG · 2011 to 2020
$3.3M
NCI NIH HHS P30 CA008748NIGMS NIH HHS R01 GM097576NIH HHS R24 OD016474
6 · The paper itself

Abstract

Analyses across imaging modalities allow the integration of complementary spatiotemporal information about brain development, structure, and function. However, systematic atlasing across modalities is limited by challenges to effective image alignment. We combine highly spatially resolved electron microscopy (EM) and highly temporally resolved time-lapse fluorescence microscopy (FM) to examine the emergence of a complex nervous system in

Indexed as

Caenorhabditis elegansOptical ImagingAnimalsMicroscopy, ElectronMicroscopy, FluorescenceTime FactorsalignmentC. elegansdevelopmental biologyelectron microscopyfluorescence microscopymulti-modal imagingneuroscience

Identifiers

PMID35666127
PMCPMC9213002

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.