Evidence map›Paper›PMID 35666336›Full record

ArticleClinical and experimental nephrology2022

Parameters affecting prognosis after hemodialysis withdrawal: experience from a single center.

Kosei Yamaguchi, Mineaki Kitamura, Takahiro Takazono, Kazuko Yamamoto, Junichiroh Hashiguchi, Takashi Harada, Satoshi Funakoshi, Hiroshi Mukae, Tomoya Nishino

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical and experimental nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Prognostication After Dialysis Withdrawal.Kidney international reports · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Kosei YamaguchiNagasaki Renal Center, Nagasaki, Japan.
Mineaki KitamuraNagasaki Renal Center, Nagasaki, Japan. minekitamura@nagasaki-u.ac.jp.ORCID http://orcid.org/0000-0002-0003-8645
Takahiro TakazonoDepartment of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Kazuko YamamotoDepartment of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Junichiroh HashiguchiNagasaki Renal Center, Nagasaki, Japan.
Takashi HaradaNagasaki Renal Center, Nagasaki, Japan.
Satoshi FunakoshiNagasaki Renal Center, Nagasaki, Japan.
Hiroshi MukaeDepartment of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Tomoya NishinoDepartment of Nephrology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Nagasaki Medical Center · JPNagasaki University Hospital · JPNagasaki University · JPUniversity of Nagasaki · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWithdrawal from maintenance hemodialysis is unavoidable in some patients due to their poor general condition; however, their survival days vary depending on their health status. The factors associated with life prognosis in the terminal phase in patients undergoing hemodialysis remain unclear.

methodsPatients who died after withdrawal from hemodialysis between 2011 and 2021 at Nagasaki Renal Center were included. Patient background data were collected, and the association between the patients' clinical features and survival duration was analyzed.

resultsThe withdrawal group included 174 patients (79.8 ± 10.8 years old; 50.6% male; median dialysis vintage, 3.6 years). The most common reason for withdrawal (95%) was that hemodialysis was more harmful than beneficial because of the patient's poor general condition. The median time from withdrawal to death was 4 days (interquartile range, 3-10 days). Multivariable Cox proportional regression analysis showed that oral nutrition (hazard ratio (HR), 1.98; 95% confidence interval (CI), 1.12-3.50; P = 0.03), hypoxemia (HR, 2.32; 95% CI, 1.55-3.47; P < 0.01), ventilator use (HR, 0.26; 95% CI, 0.11-0.58; P < 0.01), and pleural effusion (HR, 1.54; CI, 1.01-2.37; P = 0.04) were associated with increased survival duration. In contrast, antibiotics and vasopressor administration were not associated with the survival duration.

conclusionIn this study, we explored the parameters affecting the survival of patients who withdrew from hemodialysis. Physicians could use our results to establish more accurate predictions, which may help the patient and their family to emotionally accept and implement the desired care plan.

Indexed as

Kidney Failure, ChronicRenal DialysisAgedAged, 80 and overAnti-Bacterial AgentsFemaleHumansMalePrognosisRetrospective StudiesRisk FactorsAnti-Bacterial AgentsEnd-stage kidney diseaseForgoingHemodialysisWithdrawal

Identifiers

PMID35666336
OpenAlexW4281924457

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.