Evidence map›Paper›PMID 35674932›Full record

ReviewHead and neck pathology2022

Extranodal MALT Lymphoma in the Oral Cavity: A Series of Three Cases with Review of Literature.

Ramandeep Kaur, Dhanlaxmi Shetty, Bhausaheb P Bagal, Sumeet Gujral, Manju Sengar, Siddhartha Laskar, Lingaraj Nayak, Tanuja Shet

Open access · greenAbstract readReview
In one paragraph

Review in Head and neck pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ramandeep KaurTata Memorial Hospital, Dr E.B. Road, Parel, Mumbai, Maharashtra, 400012, India.
Dhanlaxmi ShettyTata Memorial Hospital, Dr E.B. Road, Parel, Mumbai, Maharashtra, 400012, India.
Bhausaheb P BagalTata Memorial Hospital, Dr E.B. Road, Parel, Mumbai, Maharashtra, 400012, India.
Sumeet GujralTata Memorial Hospital, Dr E.B. Road, Parel, Mumbai, Maharashtra, 400012, India.
Manju SengarTata Memorial Hospital, Dr E.B. Road, Parel, Mumbai, Maharashtra, 400012, India.
Siddhartha LaskarTata Memorial Hospital, Dr E.B. Road, Parel, Mumbai, Maharashtra, 400012, India.
Lingaraj NayakTata Memorial Hospital, Dr E.B. Road, Parel, Mumbai, Maharashtra, 400012, India.
Tanuja ShetTata Memorial Hospital, Dr E.B. Road, Parel, Mumbai, Maharashtra, 400012, India. tanujashet5@gmail.com.ORCID http://orcid.org/0000-0001-9294-9704
Tata Memorial Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiagnosis of MALT lymphoma in the oral cavity is challenging. There is a great overlap in the histopathologic, immuno-histochemical and molecular features of MALT lymphoma with reactive lymphoid proliferations. The literature shows a very few case reports of primary MALT lymphoma of oral cavity.

methodsWe discuss the histopathologic, immuno-histochemical, cytogenetic features, treatment and behavior of 3 cases of primary MALT lymphoma oral cavity along with review of literature.

resultsThe age ranged from 40 to 57 years (male to female ratio = 2:1). The sites involved were hard palate, bilateral gingivobuccal sulcus and right buccal mucosa. The most common histology was centrocyte-like (2 cases). Lymphoepithelial lesions were absent. On immunohistochemistry, all tumors showed diffuse strong CD20 and bcl2 expression with strong and diffuse MNDA staining in one case. IgH; MALT1 translocation was not seen in any of these cases. One patient received local radiotherapy, one received steroids; while the case 3 received RCHOP (Rituximab, cyclophosphamide, hydroxydaunorubicin hydrochloride, vincristine and prednisone) chemotherapy. Two patients had complete remission while one had recurrence.

conclusionMALT lymphoma of oral cavity shows a wide spectrum of morphology with presence of transformed cells, that may lead to misdiagnosis of DLBL. Treatment guidelines are not well established but a tendency to excise MALT lymphomas of oral cavity has been observed. Nevertheless, MALT lymphoma of oral cavity appears to be an indolent disease.

Indexed as

Lymphoma, B-Cell, Marginal ZoneAdultFemaleHumansMaleMiddle AgedMouthBehaviorCytogeneticsExtranodalMALT lymphomaOral cavityPrimary

Identifiers

PMID35674932
PMCPMC9729474
OpenAlexW4282925847

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.