Evidence mapPaperPMID 35676007Full record

ArticleBMJ open2022

Effect of non-pharmacological interventions for overweight/obese women with polycystic ovary syndrome on ovulation and pregnancy outcomes: a protocol for a systematic review and network meta-analysis.

Han Yang, Yan-Qun Xiao, Jia-Jia Liu, Gui-Xing Xu, Juan Li, Zhi-Yong Xiao, Jun Zhou, Xiao-Yan Zheng, Li-Ying Liu, Zheng Yu and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Han Yang *Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.ORCID 0000-0002-0939-2392
Yan-Qun Xiao *Infertility Clinic, Chengdu Xinan Gynecological Hospital, Chengdu, China.
Jia-Jia Liu *Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Gui-Xing XuAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Juan LiSchool of Health Preservation and Rehabilitation, Traditional Chinese Medicine of Chengdu University, Chengdu, Sichuan, China.ORCID 0000-0002-8530-9001
Zhi-Yong XiaoAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jun ZhouAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Xiao-Yan ZhengAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.ORCID 0000-0002-2740-7076
Li-Ying LiuAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.ORCID 0000-0001-8943-6203
Zheng YuCollege of Medical Information and Engineering, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jie YangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Fan-Rong LiangAcupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China acuresearch@126.com.ORCID 0000-0001-8518-9268
Chengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMost overweight/obese women with polycystic ovary syndrome (PCOS) have infertility issues which are difficult to treat. Non-pharmacological interventions used for the management of infertility include lifestyle interventions, acupuncture therapies and nutritional supplements. These interventions have been reported to be beneficial in alleviating infertility among overweight women with PCOS. However, effect and safety of these non-pharmacological interventions vary, and there is no standard method of clinical application. Therefore, it is necessary to conduct a systematic review and network meta-analysis (NMA) to rank these non-pharmacological interventions in terms of effect and determine which one is more effective for clinical application. METHODS AND ANALYSIS: We will retrieve eight databases including Cochrane Library, Medline, Embase, PsycINFO, Chinese National Knowledge Infrastructure, WanFang Data, the Chongqing VIP Database and China Biology Medicine disc from their inceptions onwards. In addition, four clinical trial registries and the related references will be manually retrieved. The primary outcome will be clinical pregnancy. Live birth, ovulation, pregnancy loss, multiple pregnancy and adverse events related to interventions will be considered as the secondary outcomes. STATA software V.15.0 and Aggregate Data Drug Information System V.1.16.8 will be used to conduct pairwise meta-analysis and NMA. The Grading of Recommendations Assessment, Development and Evaluation system will be adopted to evaluate the certainty of evidence. ETHICS AND DISSEMINATION: Ethical approval will not be required because the study will not include the original information of participants. The results will be published in a peer-reviewed journal or disseminated in relevant conferences. PROSPERO REGISTRATION NUMBER: CRD42021283110.

Indexed as

InfertilityPolycystic Ovary SyndromeFemaleHumansNetwork Meta-Analysis as TopicObesityOverweightOvulationPregnancySystematic Reviews as TopicCOMPLEMENTARY MEDICINEReproductive medicineSubfertility

Identifiers

PMID35676007
PMCPMC9185587
OpenAlexW4281788151

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.