Evidence map›Paper›PMID 35676644›Full record

ArticleBMC geriatrics2022

Medicines use before and after comprehensive medicines review among residents of long-term care facilities: a retrospective cohort study.

Janet K Sluggett, Gillian E Caughey, Tracy Air, Max Moldovan, Catherine Lang, Grant Martin, Stephen R Carter, Shane Jackson, Andrew C Stafford, Steve L Wesselingh and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Janet K SluggettUniversity of South Australia, UniSA Allied Health and Human Performance, GPO Box 2471, Adelaide, South Australia, Australia. janet.sluggett@unisa.edu.au.
Gillian E CaugheyUniversity of South Australia, UniSA Allied Health and Human Performance, GPO Box 2471, Adelaide, South Australia, Australia.
Tracy AirRegistry of Senior Australians, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Max MoldovanRegistry of Senior Australians, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Catherine LangRegistry of Senior Australians, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Grant MartinAustralian Association of Consultant Pharmacy, Australian Capital Territory, Fyshwick, Australia.
Stephen R CarterSchool of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Shane JacksonSchool of Pharmacy and Pharmacology, University of Tasmania, Hobart, TAS, Australia.
Andrew C StaffordCurtin Medical School, Faculty of Health Sciences, Curtin University, Perth, WA, Australia.
Steve L WesselinghRegistry of Senior Australians, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
Maria C InacioUniversity of South Australia, UniSA Allied Health and Human Performance, GPO Box 2471, Adelaide, South Australia, Australia.
South Australian Health and Medical Research Institute · AUUniversity of South Australia · AUACT GovernmentCurtin University · AUUniversity of Sydney · AUUniversity of Tasmania · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResidential Medication Management Review (RMMR) is a subsidized comprehensive medicines review program for individuals in Australian residential aged care facilities (RACFs). This study examined weekly trends in medicines use in the four months before and after an RMMR and among a comparison group of residents who did not receive an RMMR.

methodsThis retrospective cohort study included individuals aged 65 to 105 years who first entered permanent care between 1/1/2012 and 31/12/2016 in South Australia, Victoria, or New South Wales, and were taking at least one medicine. Individuals with an RMMR within 12 months of RACF entry were classified into one of three groups: (i) RMMR within 0 to 3 months, (ii) 3 to 6 months, or (iii) within 6 to 12 months of RACF entry. Individuals without RMMRs were included in the comparison group. Weekly trends in the number of defined daily doses per 1000 days were determined in the four months before and after the RMMR (or assigned index date in the comparison group) for 14 medicine classes.

results113909 individuals from 1979 RACFs were included, of whom 55021 received an RMMR. Across all three periods examined, decreased use of statins and proton pump inhibitors was observed post-RMMR in comparison to those without RMMRs. Decreases in calcium channel blockers, benzodiazepines/zopiclone, and antidepressants were observed following RMMR provision in the 3-6 and 6-12 months after RACF entry. Negligible changes in antipsychotic use were also observed following an RMMR in the 6-12 months after RACF entry by comparison to those without RMMRs. No changes in use of opioids, ACE inhibitors/sartans, beta blockers, loop diuretics, oral anticoagulants, or medicines for osteoporosis, diabetes or the cognitive symptoms of dementia were observed post-RMMR.

conclusionsFor six of the 14 medicine classes investigated, modest changes in weekly trends in use were observed after the provision of an RMMR in the 6-12 months after RACF entry compared to those without RMMRs. Findings suggest that activities such as medicines reconciliation may be prioritized when an RMMR is provided on RACF entry, with deprescribing more likely after an RMMR the longer a resident has been in the RACF.

Indexed as

Assisted Living FacilitiesHomes for the AgedAgedHumansLong-Term CareRetrospective StudiesVictoriaAustraliaDrug utilizationHomes for the agedLong-term careMedication reviewMedication therapy managementNursing homesPharmacistsResidential aged careResidential facilities

Identifiers

PMID35676644
PMCPMC9178815
OpenAlexW4282939018

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.