Evidence map›Paper›PMID 35677697›Full record

ArticleFrontiers in cardiovascular medicine2022

Case Report: Supernormal Vascular Aging in Leningrad Siege Survivors.

Oxana Rotar, Maria Boyarinova, Ekaterina Moguchaya, Kristina Tolkunova, Nikita Kolosov, Valeriia Rezapova, Olga Freylikhman, Dmitrii Usoltsev, Olesya Melnik, Alexey Sergushichev and 9 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Decoding Vascular Senescence: Cellular Insights and Therapeutic Strategies.International journal of biological sciences · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Oxana RotarAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Maria BoyarinovaAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Ekaterina MoguchayaAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Kristina TolkunovaAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Nikita KolosovAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Valeriia RezapovaAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Olga FreylikhmanAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Dmitrii UsoltsevAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Olesya MelnikAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Alexey SergushichevITMO University, Saint Petersburg, Russia.
Vladislav SolntsevAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Anna KostarevaAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Elena DubininaHerzen State Pedagogical University of Russia, Saint Petersburg, Russia.
Trudy VoortmanErasmus Medical Center, Rotterdam, Netherlands.
Christine StevensProgram in Medical and Population Genetics, Broad Institute, Cambridge, MA, United States.
Mark J DalyProgram in Medical and Population Genetics, Broad Institute, Cambridge, MA, United States.
Alexandra KonradiAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Evgeny ShlyakhtoAlmazov National Medical Research Centre, Saint Petersburg, Russia.
Mykyta ArtomovAlmazov National Medical Research Centre, Saint Petersburg, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related changes in the vascular system play an important role in the biological age and lifespan of a person and maybe affected from an early age onward. One of the indicators of changes in the vascular system is arterial wall stiffness and its main measure, i.e., carotid-femoral pulse wave velocity (cfPWV). We examined arterial wall stiffness in a sample of 305 Leningrad Siege survivors to assess how hunger and stressful conditions during fetal development and early childhood affected the state of the cardiovascular system at a later age and what factors may neutralize the negative impact sustained in early childhood. Here, we presented an evaluation of two unique patients with supernormal vascular aging (SUPERNOVA) phenotype from this cohort and described the details of congruence between hereditary resistance and practiced lifestyle yielding slower biological aging rate.

Indexed as

agingdeep phenotypingpulse wave velocity (PWV)starvationsupernormal vascular aging

Identifiers

PMID35677697
PMCPMC9170230

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.