Evidence map›Paper›PMID 35677967›Full record

Trial reportJournal of diabetes science and technology2024

Evaluation of Effects of Continuous Glucose Monitoring on Physical Activity Habits and Blood Lipid Levels in Persons With Type 1 Diabetes Managed With Multiple Daily Insulin Injections: An Analysis Based on the GOLD Randomized Trial (GOLD 8).

Thomas Nyström, Erik Schwarz, Sofia Dahlqvist, Magnus Wijkman, Magnus Ekelund, Helen Holmer, Jan Bolinder, Jarl Hellman, Henrik Imberg, Irl B Hirsch and 1 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of diabetes science and technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 11 institutions in 2 countries.

Thomas NyströmDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-3462-7990
Erik SchwarzDepartment of Internal Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Sofia DahlqvistDepartment of Medicine, NU-Hospital Group, Uddevalla, Sweden.
Magnus WijkmanDepartment of Internal Medicine and Department of Medical and Health Sciences, Linköping University, Norrköping, Sweden.
Magnus EkelundDepartment of Clinical Sciences, Lund University, Lund, Sweden.
Helen HolmerDepartment of Internal Medicine, Centralsjukhuset, Kristianstad, Sweden.
Jan BolinderDepartment of Medicine, Karolinska University Hospital Huddinge, Karolinska Institutet, Stockholm, Sweden.
Jarl HellmanDepartment of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden.
Henrik ImbergStatistiska Konsultgruppen, Gothenburg, Sweden.
Irl B HirschSchool of Medicine, University of Washington, Seattle, WA, USA.ORCID 0000-0003-1675-8417
Marcus LindDepartment of Medicine, NU-Hospital Group, Uddevalla, Sweden.ORCID 0000-0002-3796-9283
Centralsjukhuset Kristianstad · SEChalmers University of Technology · SEKarolinska Institutet · SEKarolinska University Hospital · SELinköping University · SELund University · SENU Hospital Group · SEÖrebro University · SESahlgrenska University Hospital · SEUniversity of Washington · USUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople with type 1 diabetes generally view it easier to exercise when having continuous information of the glucose levels. We evaluated whether patients with type 1 diabetes managed with multiple daily insulin injections (MDI) exercised more after initiating continuous glucose monitoring (CGM) and whether the improved glycemic control and well-being associated with CGM translates into improved blood lipids and markers of inflammation.

methodThe GOLD trial was a randomized cross-over trial over 16 months where patients used either CGM or capillary self-monitoring of blood glucose (SMBG) over six months, with a four-month wash-out period between the two treatment periods. We compared grade of physical activity, blood lipids, apolipoproteins, and high-sensitivity C-reactive protein (hsCRP) levels during CGM and SMBG.

resultsThere were 116 patients with information of physical activity estimated by the International Physical Activity Questionnaire (IPAQ) during both CGM and SMBG. No changes were found during CGM or SMBG, IPAQ scores 3305 versus 3878 (

conclusionAlthough many patients experience it easier to perform physical activity when monitoring glucose levels with CGM, it does not influence the amount of physical activity in persons with type 1 diabetes. Blood lipids, apolipoprotein, and hsCRP levels were similar during CGM and SMBG.

Indexed as

Diabetes Mellitus, Type 1Apolipoprotein A-IBlood GlucoseBlood Glucose Self-MonitoringContinuous Glucose MonitoringC-Reactive ProteinExerciseGlycated HemoglobinHumansHypoglycemic AgentsInsulinLipidsApolipoprotein A-IBlood GlucoseC-Reactive ProteinGlycated HemoglobinHypoglycemic AgentsInsulinLipidsblood lipidscontinuous glucose monitoringhypoglycemialow-grade inflammationphysical activity

Identifiers

PMID35677967
PMCPMC10899843
OpenAlexW4282946252

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.