Evidence map›Paper›PMID 35680898›Full record

ReviewNature communications2022

Microfluidics for understanding model organisms.

Nolan Frey, Utku M Sönmez, Jonathan Minden, Philip LeDuc

Abstract readReview
In one paragraph

Review in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Live Imaging of Grass Roots Growth Dynamics Using Microfluidics.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  2. Review
  3. Review
  4. Article
  5. LFC-Lab on a chip · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Automated Platforms inMicromachines · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Periodic Flows in Microfluidics.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nolan FreyDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-1889-1724
Utku M SönmezDepartment of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA.
Jonathan MindenDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, USA. minden@andrew.cmu.edu.ORCID http://orcid.org/0000-0003-3175-393X
Philip LeDucDepartment of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA. prl@andrew.cmu.edu.ORCID http://orcid.org/0000-0002-5342-8567

Funding

Role of extracellular matrix in age-related declines of muscle regenerationR01AG061005 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AMBROSIO, FABRISIA, LEDUC, PHILIP R · 2019 to 2023
$2.5M
NIA NIH HHS R01 AG061005
6 · The paper itself

Abstract

New microfluidic systems for whole organism analysis and experimentation are catalyzing biological breakthroughs across many fields, from human health to fundamental biology principles. This perspective discusses recent microfluidic tools to study intact model organisms to demonstrate the tremendous potential for these integrated approaches now and into the future. We describe these microsystems' technical features and highlight the unique advantages for precise manipulation in areas including immobilization, automated alignment, sorting, sensory, mechanical and chemical stimulation, and genetic and thermal perturbation. Our aim is to familiarize technologically focused researchers with microfluidics applications in biology research, while providing biologists an entrée to advanced microengineering techniques for model organisms.

Indexed as

Microfluidic Analytical TechniquesMicrofluidicsHumans

Identifiers

PMID35680898
PMCPMC9184607

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.